Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA
Wojtaszek, J. L., Hoff, K. E., Longley, M. J., Kaur, P., Andres, S. N., Wang, H., … Copeland, W. C. (2023, August 18). NUCLEIC ACIDS RESEARCH.
TL;DR:
Data indicate that PolG2 DNA binding has both PolG-dependent and -independent functions in mitochondrial DNA replication and maintenance, which provide new insight into molecular defects associated with PolG 2 disruption in mitochondrial disease.
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