Local Identifiability Analysis, Parameter Subset Selection and Verification for a Minimal Brain PBPK Model
Bulletin of Mathematical Biology.
TL;DR:
This work introduces the use of a local sensitivity-based parameter subset selection algorithm in the context of a minimal PBPK (mPBPK) model of the brain for antibody therapeutics to provide a systematic and robust technique to determine identifiable parameter subsets in a PBPK model across a specified time domain of interest.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)