2022 journal article

Cite it

Precision Guided Sterile Males Suppress Populations of an Invasive Crop Pest

GEN Biotechnology, 1(4), 372–385.

By: N. Kandul ^*, J. Liu ^*, A. Buchman ^*, I. Shriner ^*, R. Corder ^*, N. Warsinger-Pepe ^*, T. Yang ^*, A. Yadav  ⁿ ...and 3 other authors, including 1 NC State author, M. Scott ⁿ , J. Marshall ^* & O. Akbari ^*

Contributors: M. Scott ⁿ 

TL;DR: Precision guided sterile insect technique (pgSIT) utilizes the accuracy of programmable CRISPR gene targeting to generate sterilized males that can be deployed to suppress populations. (via Semantic Scholar)

10.1089/genbio.2022.0019

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UN Sustainable Development Goal Categories

2. Zero Hunger (OpenAlex)

Source: ORCID

Added: January 29, 2024

The Drosophila suzukii invasion of western countries has created an immense agricultural and economic threat to crop production. Despite many attempts to suppress its population, D. suzukii continues to destroy soft-flesh fruits. Precision guided sterile insect technique (pgSIT) utilizes the accuracy of programmable CRISPR gene targeting to generate sterilized males that can be deployed to suppress populations. Here, we generate pgSIT in D. suzukii and empirically and mathematically demonstrate that sterilized males are fit, competitive, and can eliminate populations of D. suzukii . Alto-gether, we describe an efficient way to generate sterile D. suzukii for release and safe effective population suppression.