2023 journal article
Enteric glial cell network function is required for epithelial barrier restitution following intestinal ischemic injury in the early postnatal period
American Journal of Physiology-Gastrointestinal and Liver Physiology.
This study refines a powerful translational pig model, defining an age-dependent relationship between enteric glia and the intestinal epithelium during intestinal ischemic injury and confirming an important role for enteric glial cell (EGC) activity in driving mucosal barrier restitution. This study suggests that targeting the enteric glial network could lead to novel interventions to improve recovery from intestinal injury in neonatal patients.