Association of orthodenticle with Natural Variation for Early Embryonic Patterning in Drosophila melanogaster
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, 312B(8), 841–854.
MeSH headings : Animals; Animals, Genetically Modified; Base Sequence; Body Patterning; DNA Primers; Drosophila Proteins / genetics; Drosophila melanogaster / embryology; Drosophila melanogaster / genetics; Enhancer Elements, Genetic; Female; Gene Expression; Haplotypes; Homeodomain Proteins / genetics; In Situ Hybridization; Molecular Sequence Data; Polymorphism, Genetic; Sequence Homology, Nucleic Acid
TL;DR:
It is demonstrated that even a process as robust as early developmental patterning is affected by standing genetic variation, intriguingly involving otd, whose morphogenetic function bicoid is thought to have displaced during dipteran evolution.
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