author keywords: cocaine; sexual differentiation; mice; sex chromosomes; dopamine; estrogen

MeSH headings : Aging / drug effects; Aging / physiology; Animals; Brain / drug effects; Brain / physiology; Gonadal Steroid Hormones / pharmacology; Humans; Reward; Risk Factors; Sex Characteristics; Sex Differentiation / physiology; Sex Factors; Substance-Related Disorders / epidemiology; Substance-Related Disorders / etiology

TL;DR: It is proposed that sex chromosome complement also plays a role in determining sex-specific drug-taking behavior and the four core genotypes mouse model is proposed as an effective tool for answering these questions. (via Semantic Scholar)