Chromosomal tet(O)-Harboring Regions in Campylobacter coli Isolates from Turkeys and Swine
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(23), 8488–8491.
MeSH headings : Animals; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Carrier Proteins / genetics; Chromosomes, Bacterial; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Insertional; Poultry Diseases / microbiology; Sequence Analysis, DNA; Swine; Swine Diseases / microbiology; Tetracycline Resistance; Turkeys
TL;DR:
In turkey-derived Campylobacter coli isolates of a unique lineage (cluster II), the tetracycline resistance determinant tet(O) was chromosomal and was part of a gene cassette (transposon) interrupting a Campyloblacter jejuni-associated putative citrate transporter gene.
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ABSTRACT
In turkey-derived
Campylobacter coli
isolates of a unique lineage (cluster II), the tetracycline resistance determinant
tet
(O) was chromosomal and was part of a gene cassette (transposon) interrupting a
Campylobacter jejuni
-associated putative citrate transporter gene. In contrast, the swine-derived
C. coli
strain 6461 harbored a chromosomal
tet
(O) in a different genomic location.