The evolving role of the orphan nuclear receptor ftz-f1, a pair-rule segmentation gene
[Review of ]. EVOLUTION & DEVELOPMENT, 15(6), 406–417.
MeSH headings : Animals; Drosophila melanogaster / metabolism; Evolution, Molecular; Gene Expression Regulation, Developmental; Insect Proteins / chemistry; Insect Proteins / genetics; Insect Proteins / metabolism; Orphan Nuclear Receptors / chemistry; Orphan Nuclear Receptors / genetics; Orphan Nuclear Receptors / metabolism; Tribolium / embryology; Tribolium / genetics; Tribolium / metabolism
TL;DR:
It is proposed that the dependence of Dm‐Ftz‐F1 on interaction with the homeodomain protein Ftz which is expressed in stripes in Drosophila, loosened constraints on DM‐ftz‐f1 expression, allowing for ubiquitous expression of this pair‐rule gene in Dosophila.
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