MeSH headings : Cytochrome P-450 CYP1B1 / genetics; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Drug Interactions; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans; Neoplasms; Ruthenium

TL;DR: The creation of light-triggered CYP1B1 inhibitors as “prodrugs” are described, and achieve >6000-fold improvement in potency upon activation with low-energy (660 nm) light. (via Semantic Scholar)