2020 journal article

Avobenzone incorporation in a diverse range of Ru(<scp>ii</scp>) scaffolds produces potent potential antineoplastic agents

Dalton Transactions, 49(35), 12161–12167.

By: R. Ryan *, D. Havrylyuk* , K. Stevens*, L. Moore*, D. Kim *, J. Blackburn *, D. Heidary *, J. Selegue *, E. Glazer *

MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Line, Tumor; Coordination Complexes / chemistry; Coordination Complexes / pharmacology; Humans; Ligands; Photochemotherapy; Propiophenones / chemistry; Ruthenium / chemistry; Structure-Activity Relationship
TL;DR: Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand. (via Semantic Scholar)
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Added: January 28, 2023

Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand.