2024 journal article

Myeloid Cell MHC I Expression Drives CD8 + T Cell Activation in Nonalcoholic Steatohepatitis

Frontiers in Immunology.

Contributors: T. Williams n, V. Adams n, L. Collins n, J. Holmes n, P. Hess n, H. Atkins n, G. Scheidemantle n, X. Liu n ...

TL;DR: Activated hepatic CD8+ T cells are dependent on myeloid cell MHC class I expression in diet induced NASH to promote inflammation and fibrosis and a role of NADPH oxidase in the production of Ncf2 peptide generation is suggested. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

Activated CD8