Geminivirus VIGS of endogenous genes requires SGS2/SDE1 and SGS3 and defines a new branch in the genetic pathway for silencing in plants
PLANT JOURNAL, 38(6), 1004–1014.
author keywords: geminivirus; gene silencing; Arabidopsis; DNA VIGS; RNA-dependent RNA polymerase
MeSH headings : Arabidopsis / genetics; Arabidopsis / virology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / physiology; DNA, Viral / metabolism; Geminiviridae / physiology; Gene Expression Regulation, Plant / physiology; Gene Silencing / physiology; Mutation; Plants, Genetically Modified
TL;DR:
It is demonstrated that SGS2/SDE1 and SGS3 are needed for endogenous gene silencing from DNA viruses, and suggest that S GS2/ SDE1 may reduce geminivirus symptoms by targeting viral mRNAs.
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15. Life on Land
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