2020 journal article

Optimizing a Screening Protocol for Potential Extended-Spectrum beta-Lactamase Escherichia coli on MacConkey Agar for Use in a Global Surveillance Program


By: M. Jacob n, S. Keelara n, A. Aidara-Kane*, J. Alvarez* & P. Fedorka-Cray n

co-author countries: Switzerland 🇨🇭 United States of America 🇺🇸
author keywords: ESBL; Escherichia coli; MacConkey agar; global surveillance
MeSH headings : Agar; Anti-Bacterial Agents / pharmacology; Escherichia coli; Escherichia coli Infections / epidemiology; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Reproducibility of Results; beta-Lactamases
Source: Web Of Science
Added: October 26, 2020

The increasing prevalence of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli is worrisome. Coordinated efforts to better understand global prevalence and risk factors are needed. Developing lower- and middle-income countries need reliable, readily available, and cost-effective solutions for detecting ESBL E. coli to contribute to global surveillance. We evaluated MacConkey agar supplemented with ceftriaxone or cefotaxime as a screening method for accurately detecting and quantifying potential ESBL E. coli .