2021 article
Novel 3D-printed Electrodes for Implantable Biopotential Monitoring
2021 43RD ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY (EMBC), pp. 7120–7123.
co-author countries:
Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Electric Conductivity; Electrodes; Equipment Design; Humans; Printing, Three-Dimensional; Prostheses and Implants
ieeexplore.ieee.org (publisher PDF)
Source: Web Of Science
Added: April 25, 2022
A major bottleneck in the manufacturing process of a medical implant capable of biopotential measurements is the design and assembly of a conductive electrode interface. This paper presents the use of a novel 3D-printing process to integrate conductive metal surfaces on a low-temperature co-fired ceramic base to be deployed as electrodes for electrocardiography (ECG) implants for small animals. In order to fit the ECG sensing system within the size of an injectable microchip implant, the electronics along with a pin-type lithium-ion battery are inserted into a cylindrical glass tube with both ends sealed by these 3D printed composite electrode discs using biomedical epoxy. In the scope of this paper, we present a proof-of-concept in vivo experiment for recording ECG from an avian animal model under local anesthesia to verify the electrode performance. Simultaneous recording with a commercial device validated the measurements, demonstrating promising accuracy in heart rate and breathing rate monitoring. This novel technology could open avenues for the mass manufacturing of miniaturized ECG implants.Clinical relevance— A novel manufacturing process and an implantable system are presented for continuous physiological monitoring of animals to be used by veterinarians, animal scientists, and biomedical researchers with potential future applications in human health monitoring.
