Chengming Li

Works (21)

Updated: July 12th, 2023 12:20
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2006 journal article

Heparin and fibroblast growth factors affect surfactant protein gene expression in type II cells

American Journal of Respiratory Cell and Molecular Biology, 35(5), 611–618.

By: K. Leiner, D. Newman, C. Li, E. Walsh, J. Khosla & P. Sannes

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Heparin affects signaling pathways stimulated by fibroblast growth factor-1 and-2 in type II cells

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 287(1), L191–L200.

By: D. Newman*, C. Li*, R. Simmons*, J. Khosla* & P. Sannes*

author keywords: extracellular matrix; basement membrane; receptor tyrosine kinase phosphorylation; ERK pathway; fibroblast growth factor signaling
MeSH headings : Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Fibroblast Growth Factor 1 / pharmacology; Fibroblast Growth Factor 2 / pharmacology; Heparin / administration & dosage; Heparin / pharmacology; Mitogen-Activated Protein Kinases / metabolism; Phosphorylation / drug effects; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins / metabolism; Proto-Oncogene Proteins c-akt; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / metabolism; Pulmonary Alveoli / physiology; Rats; Rats, Inbred Strains; Signal Transduction / drug effects; Sulfates / metabolism; Thymidine / metabolism; Time Factors
Source: Web Of Science
Added: August 6, 2018

2003 article

Modulation of fibroblast growth factor expression and signal transduction in type II cells

Li, C. M., Newman, D., Cesta, M., Tompkins, L., Khosla, J., & Sannes, P. L. (2003, March). CHEST, Vol. 123, pp. 429S–429S.

By: C. Li n, D. Newman*, M. Cesta*, L. Tompkins*, J. Khosla* & P. Sannes*

MeSH headings : Antigenic Modulation / genetics; Antigenic Modulation / immunology; Asthma / genetics; Asthma / immunology; Epithelial Cells / immunology; Fibroblast Growth Factors / genetics; Fibroblast Growth Factors / immunology; Gene Expression / genetics; Gene Expression / immunology; Humans; In Vitro Techniques; Signal Transduction / genetics; Signal Transduction / immunology
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Effect of growth factor-fibronectin matrix interaction on rat type II cell adhesion and DNA synthesis

EXPERIMENTAL LUNG RESEARCH, 28(2), 69–84.

By: I. Pagan n, J. Khosla n, C. Li n & P. Sannes n

author keywords: alveolar repair; beta 1integrin; cell-substratum interaction; cytoskeleton; fibroblast growth factors; fibronectin; type II cells
MeSH headings : Actins / metabolism; Animals; Blood Proteins / pharmacology; Cell Adhesion / drug effects; Cell Division / drug effects; Cell Size / drug effects; Cells, Cultured; Cytoskeletal Proteins / metabolism; DNA / biosynthesis; Extracellular Matrix / metabolism; Fibroblast Growth Factor 1 / pharmacology; Fibroblast Growth Factor 2 / pharmacology; Fibronectins / pharmacology; Integrin beta1 / metabolism; Pulmonary Alveoli / cytology; Pulmonary Alveoli / metabolism; Rats; Rats, Inbred F344; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Heparin inhibits DNA synthesis and gene expression in alveolar type II cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 27(3), 345–352.

By: C. Li n, D. Newman*, J. Khosla* & P. Sannes*

MeSH headings : Animals; Cell Division / drug effects; Cells, Cultured; DNA / biosynthesis; DNA / drug effects; Extracellular Matrix / drug effects; Extracellular Matrix / metabolism; Fibroblast Growth Factor 1 / genetics; Fibroblast Growth Factor 1 / metabolism; Fibroblast Growth Factor 1 / pharmacology; Fibroblast Growth Factor 2 / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Heparin / pharmacology; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / physiology; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases / drug effects; Receptor Protein-Tyrosine Kinases / genetics; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor / drug effects; Receptors, Fibroblast Growth Factor / genetics; Thymidine / metabolism
Source: Web Of Science
Added: August 6, 2018

2001 article

Transforming growth factor-beta(1) modifies fibroblast growth factor-2 production in type II cells

Li, C. M., Khosla, J., Hoyle, P., & Sannes, P. L. (2001, July). CHEST, Vol. 120, pp. 60S–61S.

By: C. Li n, J. Khosla n, P. Hoyle n & P. Sannes n

author keywords: alveolar epithelium; extracellular matrix; growth factors
MeSH headings : Animals; Fibroblast Growth Factor 2 / biosynthesis; Pulmonary Alveoli / metabolism; Rats; Rats, Inbred F344; Transforming Growth Factor beta / physiology; Transforming Growth Factor beta1
Source: Web Of Science
Added: August 6, 2018

2000 journal article

TGF-beta 1 and fibroblast growth factor-1 modify fibroblast growth factor-2 production in type II cells

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 279(6), L1038–L1046.

By: C. Li n, J. Khosla n, I. Pagan n, P. Hoyle n & P. Sannes n

author keywords: basic fibroblast growth factor; acidic fibroblast growth factor; alveolar epithelium; alveolar injury; pulmonary fibrosis; transforming growth factor
MeSH headings : Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2 / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Pulmonary Alveoli / cytology; Pulmonary Alveoli / metabolism; Pulmonary Fibrosis / metabolism; RNA, Messenger / analysis; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases / genetics; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor / genetics; Specific Pathogen-Free Organisms; Transforming Growth Factor beta / pharmacology
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Development of monoclonal antibodies against bovine mucin core 2 beta 6 N-acetylglucosaminyltransferase

GLYCOCONJUGATE JOURNAL, 16(9), 555–562.

By: C. Li*, N. Joshee *, K. Adler n & P. Cheng*

author keywords: core 2 N-acetylglucosaminyltransferase; glycosyltransferase; monoclonal antibodies; mucin
MeSH headings : Animals; Antibodies, Monoclonal / biosynthesis; Blotting, Western; Cattle; Cloning, Molecular; Escherichia coli / genetics; Escherichia coli / metabolism; Fluorescent Antibody Technique; Histidine; Humans; Hybridomas / metabolism; Mice; N-Acetylglucosaminyltransferases / genetics; N-Acetylglucosaminyltransferases / immunology; Peptides / genetics; Recombinant Fusion Proteins / biosynthesis; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology
Source: Web Of Science
Added: August 6, 2018

1998 chapter

Intracellular regulation of airway mucin secretion.

In Cilia, mucus and mucociliary interactions (pp. 143–151).

By: B. Fischer, C. Li, H. Li, N. Choe, D. Wright, L. Rochelle, K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Mucin biosynthesis: Molecular cloning and expression of bovine lung mucin core 2 N-acetylglucosaminyltransferase cDNA

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 18(3), 343–352.

By: C. Li n, K. Adler n & P. Cheng n

MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Carbohydrate Sequence; Cattle; Cloning, Molecular; DNA, Complementary / genetics; Genomic Library; Immunohistochemistry; Lung / enzymology; Molecular Sequence Data; Mucins / biosynthesis; N-Acetylglucosaminyltransferases / genetics; Recombinant Proteins / biosynthesis; Research Design; Sequence Analysis, DNA; Sequence Homology, Amino Acid
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Sulfation of extracellular matrices modifies growth factor effects on type II cells on laminin substrata

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 275(4), L701–L708.

By: P. Sannes n, J. Khosla n, C. Li n & I. Pagan n

author keywords: sulfated proteoglycans; basement membrane; acidic fibroblast growth factor; basic fibroblast growth factor; keratinocyte growth factor
MeSH headings : Animals; Cell Adhesion / drug effects; Cell Division / drug effects; Cells, Cultured; Chondroitin / pharmacology; Chondroitin Sulfates / pharmacology; Chondroitin Sulfates / physiology; Extracellular Matrix / physiology; Fibroblast Growth Factor 1; Fibroblast Growth Factor 10; Fibroblast Growth Factor 2 / pharmacology; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Growth Substances / pharmacology; Growth Substances / physiology; Heparin / pharmacology; Heparin / physiology; Heparitin Sulfate / pharmacology; Heparitin Sulfate / physiology; Laminin / pharmacology; Laminin / physiology; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / physiology; Rats; Rats, Inbred F344
Source: Web Of Science
Added: August 6, 2018

1997 chapter

Interactions between oxidant gases and airway epithelial cells; in vitro in vivo correlations.

In Correlations between in vitro and in vivo investigations in inhalation toxicology. (pp. 216–229).

By: D. Wright, C. Li, B. Fischer, K. Yagaloff & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1997 article

Intracellular regulation of mucin secretion.

Proceedings of the International Congress on Cilia, Mucus and Mucociliary Interations., p. 15.

By: K. Adler, C. Li, H. Li, N. Choe & B. Fischer

Source: NC State University Libraries
Added: August 6, 2018

1997 article

Molecular cloning and expression of a mucin core 2 N-acetylglucosaminyltransferase cDNA.

American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A434.

By: P. Cheng, C. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1996 article

Nitric oxide: A key signaling molecule regulating airway mucin secretion.

Proceedings of the 9th World Congress on Bronchology & World Congress on Bronchoesophagology., Vol. 9, p. S060.

By: K. Adler, D. Wright, C. Li, H. Li, N. Choe, L. Rochell, B. Fischer

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Oxidant stress stimulates mucin secretion and PLG in airway epithelium via a nitric oxide-dependent mechanism

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 271(5), L854–L861.

By: D. Wright n, B. Fischer n, C. Li n, L. Rochelle n, N. Akley n & K. Adler n

author keywords: airway epithelial cells; second messengers; nitric oxide; phospholipase C
MeSH headings : Animals; Cell Transformation, Viral; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium / drug effects; Epithelium / physiology; Guinea Pigs; Humans; Hydrogen Peroxide / pharmacology; Molsidomine / analogs & derivatives; Molsidomine / pharmacology; Mucins / biosynthesis; Mucins / metabolism; Nitric Oxide / pharmacology; Penicillamine / analogs & derivatives; Penicillamine / pharmacology; Peroxides / pharmacology; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides / pharmacology; Trachea / physiology; Type C Phospholipases / metabolism; Xanthine Oxidase; omega-N-Methylarginine / pharmacology; tert-Butylhydroperoxide
Source: Web Of Science
Added: August 6, 2018

1995 article

Endogenously-generated nitric oxide (NO) may be a key signaling molecule in hypersecretion of mucin by guinea pig tracheal epithelial (GPTE) cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337.

By: B. Fischer, D. Wright, H. Li, C. Li, L. Cohn, N. Akley, K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1995 article

Reactive nitrogen species (RNS) stimulate secretion of mucin by primary cultures of guinea pig tracheal epithelial (GPTE) cells.

American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337.

By: D. Wright, C. Li, B. Fischer, N. Akley & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1994 article

Effects of oxidant stress on airway epithelial cells in vitro.

FASEB Journal, Vol. 8, p. A896.

By: K. Adler, D. Wright, B. Fischer, L. Cohn, C. Li, H. Li, N. Choe, N. Akley

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

Interactions of oxygen radicals with airway epithelium.

Environmental Health Perspectives. Supplements, 102(11), 85–90.

By: D. Wright n, L. Cohn n, H. Li n, B. Fischer n, C. Li n & K. Adler n

MeSH headings : Animals; Antioxidants / metabolism; Epithelium / drug effects; Epithelium / physiopathology; Humans; Oxidoreductases / metabolism; Reactive Oxygen Species / pharmacology; Respiratory System / drug effects; Respiratory System / physiopathology
Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES AGAINST GUINEA-PIG TRACHEAL MUCINS

HYBRIDOMA, 13(4), 281–287.

By: C. Li*, P. Cheng & K. Adler*

MeSH headings : Animals; Antibodies, Monoclonal / immunology; Blotting, Western; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Microscopy, Immunoelectron; Mucins / analysis; Mucins / immunology; Periodic Acid / immunology; Species Specificity; Trachea / chemistry; Trachea / immunology
Source: Web Of Science
Added: August 6, 2018