Works (22)

Updated: July 5th, 2023 16:02

2008 review

Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro

[Review of ]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 40(6-7), 1379โ€“1388.

By: K. Lin n, J. Park n, A. Crews n, Y. Li n & K. Adler n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: PAR-2; mucin; airway; secretion
MeSH headings : Bronchi / cytology; Cell Culture Techniques; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Mucins / genetics; Mucins / metabolism; Oligopeptides / chemical synthesis; Oligopeptides / chemistry; Oligopeptides / pharmacology; Papillomaviridae / physiology; RNA, Small Interfering / pharmacology; Receptor, PAR-2 / agonists; Receptor, PAR-2 / genetics; Receptor, PAR-2 / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism; Time Factors; Transfection
Source: Web Of Science
Added: August 6, 2018

2007 patent

Method and compositions for altering mucus secretion

Washington, DC: U.S. Patent and Trademark Office.

By: Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

(R)-Albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS

American Journal of Respiratory Cell and Molecular Biology, 34(1), 119โ€“127.

By: B. Chorley, Y. Li, S. Fang, J. Park & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Methods for regulating inflammatory mediators and peptides useful therein

Washington, DC: U.S. Patent and Trademark Office.

By: S. Takashi, I. Parikh, K. Adler, L. Martin & L. Y.

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism

AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651โ€“661.

By: J. Park n, F. He n, L. Martin n, Y. Li n, B. Chorley n & K. Adler n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bronchi / cytology; Bronchi / drug effects; Bronchi / metabolism; Cell Differentiation; Cells, Cultured; Enzyme Activation / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Isoenzymes / metabolism; Leukocyte Elastase / pharmacology; Mucins / metabolism; Protein Kinase C / metabolism; Protein Kinase C / physiology; Protein Kinase C-delta; Protein Kinase Inhibitors / pharmacology
Source: Web Of Science
Added: August 6, 2018

2004 journal article

A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma

NATURE MEDICINE, 10(2), 193โ€“196.

By: M. Singer*, L. Martin n, B. Vargaftig*, J. Park n, A. Gruber, Y. Li n, K. Adler n

co-author countries: Brazil ๐Ÿ‡ง๐Ÿ‡ท France ๐Ÿ‡ซ๐Ÿ‡ท United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Asthma / metabolism; Bronchi / cytology; Bronchi / metabolism; Bronchi / pathology; Bronchial Provocation Tests; Cytoplasmic Granules / metabolism; Cytoplasmic Granules / ultrastructure; Disease Models, Animal; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mucins / metabolism; Mucus / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Ovalbumin / administration & dosage; Ovalbumin / immunology; Peptide Fragments / administration & dosage; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Peptides / administration & dosage; Peptides / chemistry; Peptides / pharmacology; Proteins / chemistry; Proteins / genetics; Proteins / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
Source: Web Of Science
Added: August 6, 2018

2004 patent

Blocking peptide for inflammatory cell secretion

Washington, DC: U.S. Patent and Trademark Office.

By: L. Martin, K. Adler & Y. Li

Source: NC State University Libraries
Added: August 6, 2018

2003 article

A myristoylated peptide directed against the N-terminal region of MARCKS protein inhibits mucin secretion in ovalbumin sensitized/challenged mice in vivo.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A17.

By: B. Vargaftig, M. Singer, L. Martin, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Activation of protease-activated receptors?2 (PAR-2) is not associated with enhanced mucin secretion by well-differentiated normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A204.

By: K. Lin, J. Park, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Differential effects of albuterol isomers on normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A205.

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Human neutrophil elastase provokes release of MUC5B mucin from normal bronchial epithelial cells in vitro via a PKC-dependent mechanism.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A203.

By: J. Park, F. He, Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Airway epithelium and mucus - Intracellular signaling pathways for gene expression and secretion

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(4), 397โ€“400.

By: K. Adler n & Y. Li n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cells, Cultured; Gene Expression Regulation; Humans; Mucin-5B; Mucins / physiology; Mucus / physiology; Respiratory Mucosa / cytology; Respiratory Mucosa / physiology; Signal Transduction; Uridine Triphosphate / metabolism
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Enhanced expression of mucin genes in a guinea pig model of allergic asthma

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(5), 644โ€“651.

By: Y. Li n, L. Martin n, M. Minnicozzi n, S. Greenfeder n, J. Fine n, C. Pettersen n, B. Chorleyโ€‰ n, K. Adler n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Animals; Antineoplastic Agents / pharmacology; Asthma / physiopathology; Base Sequence; Bronchial Hyperreactivity / physiopathology; Cells, Cultured; Chemokine CCL11; Chemokines, CC / genetics; Cloning, Molecular; Conserved Sequence; Disease Models, Animal; Eosinophils / immunology; Gene Expression / physiology; Guinea Pigs; Histamine / pharmacology; Hypersensitivity / physiopathology; Inflammation Mediators / pharmacology; Molecular Sequence Data; Mucin 5AC; Mucin-2; Mucins / genetics; Ovalbumin / immunology; Ovalbumin / pharmacology; RNA, Messenger / analysis; Respiratory Mucosa / cytology; Respiratory Mucosa / physiology; Trachea / cytology; Tumor Necrosis Factor-alpha / pharmacology
Source: Web Of Science
Added: August 6, 2018

2001 article

MARCKS protein interaction with the cellular contractile machinery may regulate mucin secretion by human airway epithelium.

American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro

JOURNAL OF BIOLOGICAL CHEMISTRY, 276(44), 40982โ€“40990.

By: Y. Li*, L. Martin*, G. Spizz & K. Adler*

MeSH headings : Actins / metabolism; Amino Acid Sequence; Cyclic GMP-Dependent Protein Kinases / metabolism; Cytoplasm / metabolism; Down-Regulation; Enzyme Activation; Epithelial Cells / enzymology; Epithelial Cells / metabolism; Exocytosis; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Molecular Sequence Data; Mucins / metabolism; Myosins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C / metabolism; Proteins / physiology; Trachea / cytology; Trachea / enzymology; Trachea / metabolism
Source: Web Of Science
Added: August 6, 2018

2000 article

MARCKS protein: a key intracellular molecule controlling mucin secretion by human airway goblet cells.

American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A259.

By: Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Myristoylated alanine-rich C-kinase substrate protein: A major intracellular regulatory molecule controlling secretion of mucin by human airway goblet cells.

Chest, Vol. 117, pp. 266Sโ€“267S.

By: K. Adler, Y. Li & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism

TOXICOLOGY AND APPLIED PHARMACOLOGY, 163(3), 221โ€“230.

By: N. Jiang n, K. Dreher*, J. Dye*, Y. Li n, J. Richards*, L. Martin n, K. Adler n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: mucin; cytotoxicity; residual oil fly ash; oxidant
MeSH headings : Animals; Antioxidants / pharmacology; Carbon / toxicity; Cell Survival / drug effects; Cells, Cultured; Coal Ash; Dust / adverse effects; Epithelial Cells / drug effects; Gene Expression / drug effects; Guinea Pigs; Industrial Waste; Metals / toxicity; Mucins / biosynthesis; Mucins / genetics; Mucins / metabolism; Oxidants / pharmacology; Particulate Matter; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Trachea / cytology; Trachea / drug effects; Trachea / metabolism
Source: Web Of Science
Added: August 6, 2018

1999 article

Myristoylated alanine-rich C kinase substrate (MARCKS) is produced by human airway epithelial cells and is phosphorylated by PKC and PKG.

American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A723.

By: Y. Li, F. He, L. Martin, T. Krunkosky, T. Lincoln, T. Cornwell, K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Residual oil fly ash (ROFA) increases mucin secretion and mucin gene expression in guinea pig airway epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A888.

By: N. Jiang, K. Dreher, Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1999 article

TNF?-induced ICAM-1 expression in airway epithelium: involvement of IkB?.

American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A184.

By: T. Krunkosky, L. Martin, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1998 article

Cloning of guinea pig Muc2 cDNA and MUC2 gene expression in guinea pig airway epithelium in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 157, p. A728.

By: Y. Li, L. Martin, M. Minnicozzi & K. Adler

Source: NC State University Libraries
Added: August 6, 2018