Works (18)

Updated: February 10th, 2025 14:29

2005 journal article

Organic synthesis and bioassay of novel inhibitors of JH III epoxide hydrolase activity from fifth stadium cabbage loopers, Trichoplusia ni

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 83(2-3), 140–154.

By: R. Roe n, V. Kallapur n, R. Linderman n & F. Viviani n

author keywords: Trichoplusia ni; cabbage looper; juvenile hormone; epoxide hydrolase
topics (OpenAlex): Eicosanoids and Hypertension Pharmacology; Biochemical Acid Research Studies; Pharmacogenetics and Drug Metabolism
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2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Toxicity of novel aromatic and aliphatic organic acid and ester analogs of trypsin modulating oostatic factor to larvae of the northern house mosquito, Culex pipiens complex, and the tobacco hornworm, Manduca sexta

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 81(2), 71–84.

By: M. Vanderherchen n, M. Isherwood n, D. Thompson n, R. Linderman n & R. Roe n

author keywords: trypsin modulating oostatic factor; TMOF; insecticide; mosquito; tobacco hornworm; tobacco budworm; cotton bollworm; German cockroach
topics (OpenAlex): Insect Resistance and Genetics; Neurobiology and Insect Physiology Research; Insect and Pesticide Research
TL;DR: Eight non-peptidic chemical analogs oftrypsin modulating oostatic factor (TMOF, NH2-YDPAP6), an insect hormone inhibiting trypsin biosynthesis in mosquitoes, were synthesized based on the structure of the native peptide. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 patent

Pesticidal activity of functionalized cyclopropanes

Washington, DC: U.S. Patent and Trademark Office.

By: R. Linderman

Source: NC State University Libraries
Added: August 6, 2018

2003 patent

Pesticidal activity of functionalized alkenes

Washington, DC: U.S. Patent and Trademark Office.

By: R. Linderman

Source: NC State University Libraries
Added: August 6, 2018

2003 patent

Pesticidal activity of functionalized alkenes

Washington, DC: U.S. Patent and Trademark Office.

By: R. Linderman, R. Roe, D. Thompson & M. Vanderherehen

Source: NC State University Libraries
Added: August 6, 2018

2002 patent

Pesticidal peptides

Washington, DC: U.S. Patent and Trademark Office.

By: D. Borovsky & R. Linderman

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes.

ENVIRONMENTAL HEALTH PERSPECTIVES, 108(12), 1151–1157.

By: S. Coleman*, R. Linderman n, E. Hodgson* & R. Rose*

author keywords: chloroacetamide herbicides; human cytochrome P450; in vitro metabolism
topics (OpenAlex): Pesticide Residue Analysis and Safety; Pesticide Exposure and Toxicity
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2. Zero Hunger (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Synthesis of nanometer-sized hollow polymer capsules from alkanethiol-coated gold particles

CHEMICAL COMMUNICATIONS, (9), 775–776.

By: M. Wu n, . SA O'Neill, L. Brousseau n, W. McConnell n, D. Shultz n, R. Linderman n, D. Feldheim n

topics (OpenAlex): Polymer Surface Interaction Studies; Dendrimers and Hyperbranched Polymers; Block Copolymer Self-Assembly
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Cloning and expression of a novel juvenile hormone-metabolizing epoxide hydrolase during larval-pupal metamorphosis of the cabbage looper, Trichoplusia ni

INSECT MOLECULAR BIOLOGY, 8(1), 85–96.

By: S. Harris n, D. Thompson n, R. Linderman n, M. Tomalski* & R. Roe n

author keywords: juvenile hormone; epoxide hydrolase; cabbage looper; Trichoplusia ni
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cell Line; Cloning, Molecular; DNA, Complementary; Epoxide Hydrolases / genetics; Epoxide Hydrolases / metabolism; Fat Body; Gene Expression; Larva; Metamorphosis, Biological / physiology; Molecular Sequence Data; Moths / enzymology; Moths / genetics; Moths / physiology; Polymerase Chain Reaction; Pupa; Sesquiterpenes / metabolism; Spodoptera; Substrate Specificity
topics (OpenAlex): Neurobiology and Insect Physiology Research; Polyamine Metabolism and Applications; Viral Infectious Diseases and Gene Expression in Insects
TL;DR: A full‐length cDNA encoding for a microsomal juvenile hormone (JH)‐metabolizing epoxide hydrolase (TmEH‐1) was isolated from a cDNA library constructed from fat body of last stadium (wandering) cabbage loopers, Trichoplusia ni, at the exact developmental time of maximum JH epoxide Hydrolase activity. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Enhanced diastereoselectivity in the asymmetric Ugi reaction using a new "convertible" isonitrile

JOURNAL OF ORGANIC CHEMISTRY, 64(2), 336–337.

By: R. Linderman n, S. Binet n & . Petrich n

topics (OpenAlex): Multicomponent Synthesis of Heterocycles; Carbohydrate Chemistry and Synthesis; Traditional and Medicinal Uses of Annonaceae
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Source: Web Of Science
Added: August 6, 2018

1999 article

In vitro metabolism of alachlor by human liver microsomes and human cytochrome P450 isoforms

Coleman, S., Liu, S. M., Linderman, R., Hodgson, E., & Rose, R. L. (1999, August 30). CHEMICO-BIOLOGICAL INTERACTIONS, Vol. 122, pp. 27–39.

By: S. Coleman n, S. Liu n, R. Linderman n, E. Hodgson n & R. Rose n

author keywords: alachlor; CDEPA; human CYP; herbicides
MeSH headings : Acetamides / metabolism; Animals; Cytochrome P-450 Enzyme System / metabolism; Female; Herbicides / metabolism; Humans; In Vitro Techniques; Isoenzymes / metabolism; Male; Mice; Mice, Inbred Strains; Microsomes, Liver / metabolism; Rats; Rats, Long-Evans
topics (OpenAlex): Pharmacogenetics and Drug Metabolism; Carcinogens and Genotoxicity Assessment; Pesticide Exposure and Toxicity
TL;DR: It is demonstrated that male human liver microsomes are able to metabolize alachlor to CDEPA, a widely used pre-emergent chloroacetanilide herbicide which has been classified by the USEPA as a probable human carcinogen and 2,6-diethylbenzoquinone imine (DEBQI), a putative carcinogenic metabolite. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Basic principles and rationale for the use of insect genes in bioremediation: esterases, phosphotriesterase, cytochrome P450 and epoxide hydrolase

Reviews in Toxicology, 2(1998), 169–178.

By: R. Roe, E. Hodgson, R. Rose, D. Thompson, C. Devorshak, D. Anspaugh, R. Linderman, S. Harris, M. Tomalski

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Controlling interfacial electron-transfer kinetics of cytochrome c with mixed self-assembled monolayers

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 120(1), 225–226.

By: A. El Kasmi n, J. Wallace n, E. Bowden n, S. Binet n & R. Linderman n

topics (OpenAlex): Molecular Junctions and Nanostructures; Electrochemical Analysis and Applications; Analytical Chemistry and Sensors
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

A novel geminal diol as a highly specific and stable in vivo inhibitor of insect juvenile hormone esterase

ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 36(3), 165–179.

By: R. Roe n, D. Anspaugh n, K. Venkatesh n, R. Linderman n & D. Graves n

author keywords: acetylcholinesterase; juvenile hormone; juvenile hormone esterase
topics (OpenAlex): Neurobiology and Insect Physiology Research; Insect and Pesticide Research; Insect Utilization and Effects
TL;DR: Thio-containing and acetylenic trifluoromethyl ketones and OTPdOH-sulfone were potent inhibitors of insect juvenile hormone (JH) esterase with greater inhibitory activity than aliphatic and α,β-unsaturated homologs. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

Conformational bias by a removable substituent. Synthesis of eight-membered cyclic ethers via ring-closing metathesis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 119(29), 6919–6920.

By: R. Linderman n, J. Siedlecki n, S. ONeill & H. Sun n

topics (OpenAlex): Synthetic Organic Chemistry Methods; Chemical Synthesis and Analysis; Advanced Synthetic Organic Chemistry
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Source: Web Of Science
Added: August 6, 2018

1991 journal article

ORGANOPHOSPHORUS INHIBITORS OF INSECT JUVENILE-HORMONE ESTERASE

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 39(1), 57–73.

By: R. Linderman n, T. Tshering n, K. Venkatesh n, D. Goodlett n, W. Dauterman n & R. Roe n

topics (OpenAlex): Neurobiology and Insect Physiology Research; Insect and Pesticide Research; Insect Pheromone Research and Control
TL;DR: Three classes of organophosphorus inhibitors, O -alkyl ethylph phosphonates, enol phosphates, and α-thioalkylphosphonates have been prepared and assayed as inhibitors of insect juvenile hormone (JH) esterase. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1989 journal article

INHIBITION OF INSECT JUVENILE-HORMONE ESTERASE BY ALPHA,BETA-UNSATURATED AND ALPHA-ACETYLENIC TRIFLUOROMETHYL KETONES

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 35(3), 291–299.

By: R. Linderman n, L. Upchurch n, M. Lonikar n, K. Venkatesh n & R. Roe n

topics (OpenAlex): Synthesis and Biological Evaluation; Synthesis and Catalytic Reactions; Organic Chemistry Cycloaddition Reactions
TL;DR: This study clearly reveals that the S atom of α-thioalkyl substituted fluoroketone inhibitors has a more complex function than simply mimicking the site of unsaturation in the natural substrate. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1988 journal article

F-NMR-19 SPECTRAL EVIDENCE THAT 3-OCTYLTHIO-1,1,1-TRIFLUOROPROPAN-2-ONE, A POTENT INHIBITOR OF INSECT JUVENILE-HORMONE ESTERASE, FUNCTIONS AS A TRANSITION-STATE ANALOG INHIBITOR OF ACETYLCHOLINESTERASE

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 31(2), 187–194.

By: R. Linderman n, J. Leazer n, R. Roe n, K. Venkatesh n, B. Selinsky* & R. London*

topics (OpenAlex): Cholinesterase and Neurodegenerative Diseases; Pesticide Exposure and Toxicity; Insect and Pesticide Research
TL;DR: The fluoroketone binds to the enzyme active site in a tetrahedral form, indicating that 3-octylthio-1, 1,1,1-trifluoropropan-2-one does function as a transition state analog inhibitor of a hydrolytic enzyme. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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