2010 journal article

Genome-wide sssociation dtudy of Lp-PLA(2) sctivity and mass in the Framingham Heart Study

PLoS Genetics, 6(4).

By: S. Suchindran, D. Rivedal, J. Guyton, T. Milledge, X. Gao, A. Benjamin, J. Rowell, G. Ginsburg, J. McCarthy

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Does strong linkage disequilibrium guarantee redundant association results?

Genetic Epidemiology, 32(6), 546–552.

By: D. Nielsen n, S. Suchindran n & C. Smith n

author keywords: linkage disequilibrium; association mapping; negative correlation; case control; transmission disequilibrium
MeSH headings : Computer Simulation; Gene Frequency; Genetic Markers; Genome, Human; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
TL;DR: This work finds that in the null hypothesis situation, where there is no association between the markers and the phenotype, the relationship between LD and the correlation between association test outcomes is clear, though it is not always ideal. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

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