ShaoKaung Chang

Works (7)

Updated: July 5th, 2023 15:53

1994 journal article

PERCUTANEOUS-ABSORPTION, DERMATOPHARMACOKINETICS AND RELATED BIO-TRANSFORMATION STUDIES OF CARBARYL, LINDANE, MALATHION, AND PARATHION IN ISOLATED-PERFUSED PORCINE SKIN

TOXICOLOGY, 91(3), 269–280.

By: S. Chang n, P. Williams  n, W. Dauterman n & J. Riviere n

author keywords: PERCUTANEOUS ABSORPTION; PESTICIDE; SKIN FLAP
MeSH headings : Animals; Biotransformation; Carbaryl / pharmacokinetics; Carbaryl / toxicity; Culture Techniques; Hexachlorocyclohexane / pharmacokinetics; Hexachlorocyclohexane / toxicity; Insecticides / pharmacokinetics; Insecticides / toxicity; Malathion / pharmacokinetics; Malathion / toxicity; Microcirculation / metabolism; Parathion / pharmacokinetics; Parathion / toxicity; Perfusion; Skin / blood supply; Skin / drug effects; Skin / metabolism; Skin Absorption; Swine
TL;DR: Comparison of the metabolic data of P with previous results underscores the difference between non-recirculating and recirculating IPPSF systems in xenobiotic metabolism studies. (via Semantic Scholar)
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Added: August 6, 2018

1994 journal article

Percutaneous Absorption of Parathion and Its Metabolites, Paraoxon and p-Nitrophenol, Administered Alone or in Combination: In Vitro Flow-Through Diffusion Cell Studies

Pesticide Biochemistry and Physiology, 48(1), 56–62.

By: S. Chang n, W. Dauterman n & J. Riviere n

TL;DR: The percutaneous absorption of parathion relative to its two metabolites, paraoxon and p -nitrophenol, was studied in vitro using weanling pig skin in a flow-through diffusion cell system and both total absorption and absorption efficiency increased as the dose increased. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018

1994 journal article

Percutaneous absorption of topical parathion through porcine skin: in vitro studies on the effect of environmental perturbations

Journal of Veterinary Pharmacology and Therapeutics, 17(6), 434–439.

By: S. Chang*, C. Brownie n & J. Riviere*

MeSH headings : Animals; Environment; Female; Humidity; In Vitro Techniques; Models, Statistical; Parathion / metabolism; Parathion / toxicity; Skin / metabolism; Skin Absorption; Swine / metabolism; Temperature
TL;DR: The results suggest that the factors tested are not independent variables and must be considered interactive when used in assessing pesticide percutaneous absorption in domestic animals such as swine. (via Semantic Scholar)
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Sources: Web Of Science, Crossref
Added: August 6, 2018

1993 article

EFFECT OF HUMIDITY AND OCCLUSION ON THE PERCUTANEOUS-ABSORPTION OF PARATHION INVITRO

CHANG, S. K., & RIVIERE, J. E. (1993, January). PHARMACEUTICAL RESEARCH, Vol. 10, pp. 152–155.

By: S. Chang n & J. Riviere n

author keywords: HUMIDITY; PERCUTANEOUS ABSORPTION; PARATHION
MeSH headings : Animals; Female; Humidity; In Vitro Techniques; Parathion / administration & dosage; Parathion / pharmacokinetics; Skin / blood supply; Skin Absorption / physiology; Swine
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1993 journal article

TRANSDERMAL LONTOPHORETIC PEPTIDE DELIVERY - INVITRO AND INVIVO STUDIES WITH LUTEINIZING-HORMONE-RELEASING HORMONE

JOURNAL OF PHARMACEUTICAL SCIENCES, 82(3), 240–243.

By: M. Heit n, P. Williams  n, F. Jayes n, S. Chang n & J. Riviere n

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1. No Poverty (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1992 chapter

Transdermal penetration and metabolism of organophosphate insecticides

In Organophosphates: chemistry, fate and effects (pp. 241–253).

By: J. Riviere n & S. Chang n

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

PERCUTANEOUS-ABSORPTION OF PARATHION INVITRO IN PORCINE SKIN - EFFECTS OF DOSE, TEMPERATURE, HUMIDITY, AND PERFUSATE COMPOSITION ON ABSORPTIVE FLUX

FUNDAMENTAL AND APPLIED TOXICOLOGY, 17(3), 494–504.

By: S. Chang n & J. Riviere

MeSH headings : Animals; Diffusion; Dose-Response Relationship, Drug; Female; Humidity; In Vitro Techniques; Parathion / metabolism; Parathion / toxicity; Skin Absorption / drug effects; Swine; Temperature
TL;DR: Lower applied doses appeared to be more sensitive to changes in the environmental conditions studied, and if similar effects occur in vivo, the risk assessment calculations on percutaneous absorption should take these parameters into consideration. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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