Works (20)
Updated: July 28th, 2023 21:16
2011 article
Leflunomide pharmacokinetics after single oral administration to dogs
Singer, L. M., Cohn, L. A., Reinero, C. R., & Papich, M. G. (2011, December). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 34, pp. 609–611.
MeSH headings : Administration, Oral; Animals; Chromatography, High Pressure Liquid / veterinary; Crotonates / blood; Crotonates / pharmacokinetics; Dogs / blood; Drug Administration Schedule / veterinary; Female; Half-Life; Hydroxybutyrates; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / blood; Immunosuppressive Agents / pharmacokinetics; Isoxazoles / administration & dosage; Isoxazoles / blood; Isoxazoles / pharmacokinetics; Leflunomide; Linear Models; Nitriles; Toluidines / blood; Toluidines / pharmacokinetics
TL;DR:
Leflunomide has been used as an adjunctive therapy for dogs refractory to traditional immunosuppressive drugs and to prevent anti-allograft immune responses and all procedures were approved by the NIH Guide for the Care and Use of Laboratory Animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1997 chapter
Airway epithelial cells in asthma.
In Allergy and allergic diseases. (pp. 263–283).
Source: NC State University Libraries
Added: August 6, 2018
1995 article
Endogenously-generated nitric oxide (NO) may be a key signaling molecule in hypersecretion of mucin by guinea pig tracheal epithelial (GPTE) cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 151, p. A337.
Source: NC State University Libraries
Added: August 6, 2018
1994 chapter
Alternatives to in vivo toxicological testing of rodent airway epithelia.
In Animal test alternatives: refinement-reduction-replacement. (pp. 233–239).
Source: NC State University Libraries
Added: August 6, 2018
1994 journal article
Antioxidant scavenging by guinea pig and human airway epithelial cells in vitro: mechanisms of H2O2 clearance.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 265(10), 397–404.
Source: NC State University Libraries
Added: August 6, 2018
1994 article
Effects of oxidant stress on airway epithelial cells in vitro.
FASEB Journal, Vol. 8, p. A896.
Source: NC State University Libraries
Added: August 6, 2018
1994 article
INTERACTIONS BETWEEN RESPIRATORY EPITHELIAL-CELLS AND CYTOKINES - RELATIONSHIPS TO LUNG INFLAMMATION
CELLS AND CYTOKINES IN LUNG INFLAMMATION, Vol. 725, pp. 128–145.
MeSH headings : Animals; Asthma / physiopathology; Cytokines / physiology; Epithelial Cells; Epithelium / physiology; Humans; Inflammation / immunology; Inflammation / physiopathology; Lung / cytology; Lung / physiology; Lung / physiopathology; Respiratory Physiological Phenomena; Respiratory System / cytology; Respiratory System / physiopathology
TL;DR:
Activity of respiratory epithelial cells in vitro as sources of cytokines and inflammatory mediators is investigated, finding that production and release of these cytokines increases substantially after exposure to specific inflammatory stimuli, such as TNF or IL-1, and after viral infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1994 journal article
Interactions of oxygen radicals with airway epithelium.
Environmental Health Perspectives. Supplements, 102(11), 85–90.
MeSH headings : Animals; Antioxidants / metabolism; Epithelium / drug effects; Epithelium / physiopathology; Humans; Oxidoreductases / metabolism; Reactive Oxygen Species / pharmacology; Respiratory System / drug effects; Respiratory System / physiopathology
TL;DR:
Reactive oxygen species (ROS) have been implicated in the pathogenesis of numerous disease processes and Respiratory epithelium may be intimately involved in defense against, and pathophysiologic changes invoked by, ROS.
(via Semantic Scholar)
hdl.handle.net (repository)
Source: NC State University Libraries
Added: August 6, 2018
1993 article
Antioxidant scavenging by guinea pig and human airway epithelial cells in vitro: mechanisms of H2O2 clearance.
American Review of Respiratory Disease, Vol. 147, p. A440.
Source: NC State University Libraries
Added: August 6, 2018
1993 chapter
Study of xenobiotics and airway epithelium in vitro.
In Fiber toxicology. (pp. 171–194).
Source: NC State University Libraries
Added: August 6, 2018
1993 article
Use of air/liquid interface cultures to assess polarized responses of airway epithelium to toxicants.
In Vitro Cellular & Developmental Biology. Animal, Vol. 29A, p. 46A.
Source: NC State University Libraries
Added: August 6, 2018
1993 article
Use of air/liquid interface guinea pig tracheal epithelial cell culture systems for assessment of interactions between inhaled substances and airways.
Proceedings of the Toxicology Forum 1993., Vol. 1993.
Source: NC State University Libraries
Added: August 6, 2018
1992 article
Guinea pig tracheal epithelial cells in primary air/liquid interface culture scavenge H2O2 via a mechanism only partially dependent on catalase and the glutathione system.
FASEB Journal, Vol. 6, p. A939.
Source: NC State University Libraries
Added: August 6, 2018
1992 journal article
INFLAMMATORY MEDIATORS AND THE GENERATION AND RELEASE OF REACTIVE OXYGEN SPECIES BY AIRWAY EPITHELIUM INVITRO
CHEST, 101(3), S53–S54.
MeSH headings : Animals; Cells, Cultured; Endothelins / pharmacology; Epithelium / metabolism; Guinea Pigs; Hydrogen Peroxide / metabolism; Platelet Activating Factor / pharmacology; Trachea / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1992 review
INTERACTIONS BETWEEN AIRWAY EPITHELIUM AND MEDIATORS OF INFLAMMATION
[Review of ]. EXPERIMENTAL LUNG RESEARCH, 18(3), 299–322.
MeSH headings : Bronchi / metabolism; Epithelial Cells; Epithelium / metabolism; Humans; Inflammation / metabolism; Trachea / metabolism
TL;DR:
Recent studies have indicated that airway epithelial cells also can act as "effector" cells, responding to a variety of exogenous and/or endogenous stimuli by generating and releasing additional mediators of inflammation, such as eicosanoids, reactive oxygen species, and cytokines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1991 article
INVITRO STUDIES OF MECHANISMS OF LUNG INJURY IN THE RODENT
TOXICOLOGIC PATHOLOGY, Vol. 19, pp. 419–427.
author keywords: RESPIRATORY EPITHELIUM; INVITRO RESPONSE; AIRWAY RESPONSE
MeSH headings : Animals; Cells, Cultured; Epithelium / drug effects; Guinea Pigs; Lung / cytology; Lung / drug effects; Mice; Organ Culture Techniques; Rats; Trachea / drug effects
TL;DR:
Several procedures which enhance the differentiated state have been evaluated, which include maintenance on more physiologically-relevant substrata, such as collagen gels, use of defined serum-free medium and use of air/liquid interface systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1991 article
In vitro studies on mechanisms of lung injury in the rodent.
Proceedings of the 10th International Symposium of Society of Toxicological Pathologists, Vol. 10.
Source: NC State University Libraries
Added: August 6, 2018
1991 journal article
Intrahepatic Postsinusoidal Venous Obstruction in a Dog
Journal of Veterinary Internal Medicine, 5(6), 317–321.
MeSH headings : Animals; Blood Pressure; Budd-Chiari Syndrome / diagnosis; Budd-Chiari Syndrome / diagnostic imaging; Budd-Chiari Syndrome / veterinary; Dog Diseases / diagnosis; Dog Diseases / diagnostic imaging; Dogs; Female; Hepatic Veins / diagnostic imaging; Hepatic Veins / pathology; Hepatic Veins / physiopathology; Liver / diagnostic imaging; Liver / pathology; Manometry / veterinary; Radiography; Ultrasonography
TL;DR:
Intrahepatic postsinusoidal obstruction, similar to congenital Budd-Chiari syndrome in human patients, was diagnosed in a young Basenji dog.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
1991 journal article
THE INFLUENCE OF CORTICOSTEROIDS ON HOST DEFENSE-MECHANISMS
JOURNAL OF VETERINARY INTERNAL MEDICINE, 5(2), 95–104.
MeSH headings : Adrenal Cortex Hormones / pharmacology; Adrenal Cortex Hormones / physiology; Animals; Antibody Formation / drug effects; Humans; Immunity / drug effects; Immunity, Cellular / drug effects; Leukocytes / drug effects; Phagocytosis / drug effects
TL;DR:
This literature review examines the affects of corticosteroids on leukocyte kinetics, phagocytic immunity, cell-mediated immunity, and humoral immunity in steroid-resistant species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1990 journal article
Bone fragility in a kitten: An osteogenesis imperfecta-like syndrome
Journal of the American Veterinary Medical Association, 197(1), 98.
Source: NC State University Libraries
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
