Works (1)
Updated: July 5th, 2023 15:53
1991 journal article
MORPHOLOGICAL ABNORMALITIES, NEONATAL-MORTALITY, AND REPRODUCTIVE ABNORMALITIES IN MICE TRANSGENIC FOR DIPHTHERIA-TOXIN GENES THAT ARE DRIVEN BY THE PROMOTER FOR ADIPOCYTE LIPID-BINDING PROTEIN
DEVELOPMENTAL GENETICS, 12(5), 371–379.
author keywords: GENETIC ABLATION; CONGENITAL ABNORMALITIES; TRANSGENIC MICE; CELL DEATH
MeSH headings : Animals; Animals, Newborn; Carrier Proteins / genetics; Carrier Proteins / metabolism; Congenital Abnormalities / genetics; Diphtheria Toxin / genetics; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids / metabolism; Mice; Mice, Transgenic; Mortality; Mutation; Neoplasm Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Reproduction / genetics
TL;DR:
Results suggest that the transgenic mice are expressing the transgenes in cells other than adipocytes and that the aberrant production of functional toxin is responsible for the congenital abnormalities.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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