J. B. Luchansky

MeSH headings : Animals; Bacterial Adhesion / genetics; Bacterial Adhesion / physiology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Proteins / physiology; Caco-2 Cells / microbiology; Disease Models, Animal; Female; Gastrointestinal Tract / microbiology; Genes, Bacterial; Glycosylation; Humans; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Listeria monocytogenes / pathogenicity; Listeriosis / microbiology; Mice; Mutation; Serotyping; Teichoic Acids / metabolism; Virulence / genetics

TL;DR: A role for gtcA in the pathogenesis of gastrointestinal listeriosis in mice is demonstrated, and diminished ability of gTCA mutants to invade intestinal epithelial cells may be partly responsible for decreased gastrointestinal virulence. (via Semantic Scholar)

author keywords: LACTOBACILLUS; PROBES; POLYMORPHISMS

MeSH headings : Chromosomes, Bacterial; Cloning, Molecular; DNA Probes; DNA Restriction Enzymes; DNA, Bacterial / genetics; Genome, Bacterial; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus acidophilus / classification; Lactobacillus acidophilus / genetics; Nucleic Acid Hybridization; Plasmids; Polymorphism, Genetic; Transformation, Genetic

TL;DR: Identification of DNA probes and establishment of a host-vector cloning system have facilitated efforts to characterize the Lactobacillus chromosome and to distinguish between closely related species thought to be important inhabitants of the gastrointestinal tract. (via Semantic Scholar)