1992 journal article

EFFECTS OF AFB1 EMBRYONIC EXPOSURE ON CHICKEN MONONUCLEAR PHAGOCYTIC CELL FUNCTIONS

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 16(2-3), 187–196.

By: D. Neldonortiz n & M. Qureshi n

author keywords: AFLATOXIN-B(1); EMBRYONIC EXPOSURE; MONONUCLEAR PHAGOCYTIC SYSTEM FUNCTION
MeSH headings : Aflatoxin B1 / pharmacology; Aflatoxin B1 / toxicity; Age Factors; Animals; Cells, Cultured; Chick Embryo; Immunologic Deficiency Syndromes / chemically induced; Leukocyte Count / drug effects; Macrophages / drug effects; Mycotoxicosis / etiology; Mycotoxicosis / immunology; Phagocytosis / drug effects
TL;DR: It is suggested that long-term immune depression of macrophage-mediated functions can occur following embryonic exposure to AFB1, which caused a dose-related increase in embryonic mortality. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1992 journal article

THE EFFECTS OF DIRECT AND MICROSOMAL ACTIVATED AFLATOXIN-B1 ON CHICKEN PERITONEAL-MACROPHAGES INVITRO

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 31(1-2), 61–76.

By: D. Neldonortiz n & M. Qureshi n

MeSH headings : Aflatoxin B1 / immunology; Animals; Cell Adhesion / immunology; Cells, Cultured; Chickens; Female; Macrophages / immunology; Microsomes, Liver / enzymology; Microsomes, Liver / immunology; Mixed Function Oxygenases / immunology; Peritoneal Cavity / cytology; Phagocytosis / immunology; Piperonyl Butoxide
TL;DR: It is suggested that microsomal activated AFB1 causes significant alterations in chicken macrophage functions as well as piperonyl butoxide (a P-450 inhibitor) abrogated AFB1-MFO induced alterations. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1991 journal article

DIRECT AND MICROSOMAL ACTIVATED AFLATOXIN-B1 EXPOSURE AND ITS EFFECTS ON TURKEY PERITONEAL MACROPHAGE FUNCTIONS INVITRO

TOXICOLOGY AND APPLIED PHARMACOLOGY, 109(3), 432–442.

By: D. Neldonortiz n & M. Qureshi n

MeSH headings : Aflatoxin B1; Aflatoxins / metabolism; Aflatoxins / toxicity; Animals; Carcinogens / metabolism; Carcinogens / toxicity; Cells, Cultured; Chromatography, Thin Layer; Immunocompetence / drug effects; Macrophages / drug effects; Microsomes, Liver / drug effects; Microsomes, Liver / metabolism; Peritoneum; Phagocytosis / drug effects; Turkeys / physiology
TL;DR: Data collected in this study suggest that turkey macrophages are resistant to the direct exposure of AFB1 and that AFB1 induced alterations in macrophage effector functions are due to metabolic activation of USAF1 by MFOs. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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