@article{khare_alali_zhang_hunter_pugh_fang_libby_adams_2010, title={Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli O157:H7 in cattle}, volume={6}, journal={BMC Veterinary Research}, author={Khare, S. and Alali, W. and Zhang, S. P. and Hunter, D. and Pugh, R. and Fang, F. C. and Libby, S. J. and Adams, L. G.}, year={2010} }
 @article{navarre_halsey_walthers_frye_mcclelland_potter_kenney_gunn_fang_libby_2005, title={Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ}, volume={56}, ISSN={["1365-2958"]}, DOI={10.1111/j.1365-2958.2005.04553.x}, abstractNote={Summary}, number={2}, journal={MOLECULAR MICROBIOLOGY}, author={Navarre, WW and Halsey, TA and Walthers, D and Frye, J and McClelland, M and Potter, JL and Kenney, LJ and Gunn, JS and Fang, FC and Libby, SJ}, year={2005}, month={Apr}, pages={492–508} }
 @article{bruno-barcena_andrus_libby_klaenhammer_hassan_2004, title={Expression of a heterologous manganese superoxide dismutase gene in intestinal lactobacilli provides protection against hydrogen peroxide toxicity}, volume={70}, ISSN={["1098-5336"]}, url={http://europepmc.org/abstract/med/15294805}, DOI={10.1128/AEM.70.8.4702-4710.2004}, abstractNote={ABSTRACT}, number={8}, journal={APPLIED AND ENVIRONMENTAL MICROBIOLOGY}, author={Bruno-Barcena, JM and Andrus, JM and Libby, SL and Klaenhammer, TR and Hassan, HM}, year={2004}, month={Aug}, pages={4702–4710} }
 @article{halsey_vazquez-torres_gravdahl_fang_libby_2004, title={The ferritin-like Dps protein is required for Salmonella enterica serovar typhimurium oxidative stress resistance and virulence}, volume={72}, ISSN={["1098-5522"]}, DOI={10.1128/IAI.72.2.1155-1158.2004}, abstractNote={ABSTRACT}, number={2}, journal={INFECTION AND IMMUNITY}, author={Halsey, TA and Vazquez-Torres, A and Gravdahl, DJ and Fang, FC and Libby, SJ}, year={2004}, month={Feb}, pages={1155–1158} }
 @article{schapiro_libby_fang_2003, title={Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress}, volume={100}, ISSN={["0027-8424"]}, DOI={10.1073/pnas.1033133100}, abstractNote={
            Phagocytic cells inhibit the growth of intracellular pathogens by producing
 nitric oxide (NO). NO causes cell filamentation, induction of the SOS
 response, and DNA replication arrest in the Gram-negative bacterium
            Salmonella enterica
            . NO also induces double-stranded chromosomal
 breaks in replication-arrested
            Salmonella
            lacking a functional RecBCD
 exonuclease. This DNA damage depends on actions of additional DNA repair
 proteins, the RecG helicase, and RuvC endonuclease. Introduction of a
            recG
            mutation restores both resistance to NO and the ability of an
 attenuated
            recBC
            mutant
            Salmonella
            strain to cause lethal
 infection in mice, demonstrating that bacterial DNA replication is inhibited
 during host–pathogen interactions. Inhibition of DNA replication during
 nitrosative stress is invariably accompanied by zinc mobilization, implicating
 DNA-binding zinc metalloproteins as critical targets of NO-related
 antimicrobial activity.
          }, number={14}, journal={PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA}, author={Schapiro, JM and Libby, SJ and Fang, FC}, year={2003}, month={Jul}, pages={8496–8501} }
 @article{libby_lesnick_hasegawa_kurth_belcher_fierer_guiney_2002, title={Characterization of the spv locus in Salmonella enterica serovar Arizona}, volume={70}, DOI={10.1128/IAI.70.6.3290.3294.2002}, abstractNote={Salmonella enterica serovar Arizona (S. enterica subspecies IIIa) is a common Salmonella isolate from reptiles and can cause serious systemic disease in humans. The spv virulence locus, found on large plasmids in Salmonella subspecies I serovars associated with severe infections, was confirmed to be located on the chromosome of serovar Arizona. Sequence analysis revealed that the serovar Arizona spv locus contains homologues of spvRABC but lacks the spvD gene and contains a frameshift in spvA, resulting in a different C terminus. The SpvR protein functions as a transcriptional activator for the spvA promoter, and SpvB and SpvC are highly conserved. The analysis supports the proposal that the chromosomal spv sequence more closely corresponds to the ancestral locus acquired during evolution of S. enterica, with plasmid acquisition of spv genes in the subspecies I strains involving addition of spvD and polymorphisms in spvA.}, number={6}, journal={Infection and Immunity}, author={Libby, S. J. and Lesnick, M. and Hasegawa, P. and Kurth, M. and Belcher, C. and Fierer, J. and Guiney, D. G.}, year={2002}, pages={3290–3294} }
 @article{testerman_vazquez-torres_xu_jones-carson_libby_fang_2002, title={The alternative sigma factor sigma(E) controls antioxidant defences required for Salmonella virulence and stationary-phase survival}, volume={43}, ISSN={["1365-2958"]}, DOI={10.1046/j.1365-2958.2002.02787.x}, abstractNote={Summary}, number={3}, journal={MOLECULAR MICROBIOLOGY}, author={Testerman, TL and Vazquez-Torres, A and Xu, YS and Jones-Carson, J and Libby, SJ and Fang, FC}, year={2002}, month={Feb}, pages={771–782} }
 @article{wilson_libby_freet_boddicker_fahlen_jones_2001, title={Fis, a DNA nucleoid-associated protein, is involved in Salmonella typhimurium SPI-1 invasion gene expression}, volume={39}, number={1}, journal={Molecular Microbiology}, author={Wilson, R. L. and Libby, S. J. and Freet, A. M. and Boddicker, J. D. and Fahlen, T. F. and Jones, B. D.}, year={2001}, pages={79–88} }
 @article{allen_fedorka-cray_vazquez-torres_suyemoto_altier_ryder_fang_libby_2001, title={In Vitro and In Vivo Assessment of Salmonella enterica Serovar Typhimurium DT104 Virulence}, volume={69}, ISSN={0019-9567}, url={http://dx.doi.org/10.1128/iai.69.7.4673-4677.2001}, DOI={10.1128/IAI.69.7.4673-4677.2001}, abstractNote={ABSTRACT}, number={7}, journal={Infection and Immunity}, publisher={American Society for Microbiology}, author={Allen, C. A. and Fedorka-Cray, P. J. and Vazquez-Torres, A. and Suyemoto, M. and Altier, C. and Ryder, L. R. and Fang, F. C. and Libby, S. J.}, year={2001}, month={Jul}, pages={4673–4677} }
 @article{libby_lesnick_hasegawa_weidenhammer_guiney_2000, title={The Salmonella virulence plasmid spv genes are required for cytopathology in human monocyte-derived macrophages}, volume={2}, ISSN={["1462-5814"]}, DOI={10.1046/j.1462-5822.2000.00030.x}, abstractNote={The pathogenesis of serious systemic Salmonella infections is characterized by survival and proliferation of bacteria inside macrophages. Infection of human monocyte‐derived macrophages in vitro with S. typhimurium or S. dublin produces cytopathology characterized by detachment of cells that contain large numbers of proliferating bacteria. This cytopathology is dependent on the expression of the bacterial spv genes, a virulence locus previously shown to markedly enhance the ability of Salmonella to produce systemic disease. After 24 h of infection, macrophage cultures contain two populations of bacteria: (i) proliferating organisms present in a detached cell fraction; and (ii) a static bacterial population in macrophages remaining attached to the culture well. Mutations in either the essential transcriptional activator SpvR or the key SpvB protein markedly reduce the cytopathic effect of Salmonella infection. The spv‐dependent cytopathology in macrophages exhibits characteristics of apoptosis, with release of nucleosomes into the cytoplasm, nuclear condensation and DNA fragmentation. The current findings suggest that the mechanism of the spv effect is through induction of increased cytopathology in host macrophages.}, number={1}, journal={CELLULAR MICROBIOLOGY}, author={Libby, SJ and Lesnick, M and Hasegawa, P and Weidenhammer, E and Guiney, DG}, year={2000}, month={Feb}, pages={49–58} }
 @article{watson_paulin_bland_libby_jones_wallis_1999, title={Differential regulation of enteric and systemic salmonellosis by slyA}, volume={67}, number={9}, journal={Infection and Immunity}, author={Watson, P. R. and Paulin, S. M. and Bland, A. P. and Libby, S. J. and Jones, P. W. and Wallis, T. S.}, year={1999}, pages={4950–4954} }
 @article{fernandez_xing_kapur_libby_barletta_moxley_1998, title={Regulation of the Escherichia coli sheA gene and characterization of its encoded hemolytic activity}, volume={168}, ISSN={["0378-1097"]}, DOI={10.1111/j.1574-6968.1998.tb13259.x}, abstractNote={Escherichia coli K-12 carries the cryptic hemolysin gene sheA which is under the control of positive and negative transcriptional regulators. The objectives of the present study were to further analyze the regulation of the sheA gene in E. coli, to compare the sheA genes from E. coli K-12 and a pathogenic E. coli strain, and to characterize the SheA hemolytic activity. Northern blot analysis demonstrated that the transcriptional regulator SlyA activates the E. coli K-12 sheA gene. The main transcriptional start site of the sheA gene was 56 nucleotides upstream from the start codon as determined by primer extension analysis. The sheA genes from E. coli K-12 and a pathogenic E. coli strain were identical. SheA hemolytic activity was cell associated and Ca2+ independent.}, number={1}, journal={FEMS MICROBIOLOGY LETTERS}, author={Fernandez, SV and Xing, J and Kapur, V and Libby, SJ and Barletta, RG and Moxley, RA}, year={1998}, month={Nov}, pages={85–90} }
 @article{buchmeier_bossie_chen_fang_guiney_libby_1997, title={SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophages}, volume={65}, number={9}, journal={Infection and Immunity}, author={Buchmeier, N. and Bossie, S. and Chen, C. Y. and Fang, F. C. and Guiney, D. G. and Libby, S. J.}, year={1997}, pages={3725–3730} }