@article{mccall_comins_2009, title={Synthesis of 1,3-Amino Alcohol Derivatives via a Silicon-Mediated Ring-Opening of Substituted Piperidines}, DOI={10.1021/ol9010757}, abstractNote={Multisubstituted piperidines containing a trimethylsilylmethyl group at C-2 can be opened regioselectively with TBAF and cyanogen bromide. The ring-opened products contain synthetically useful cyanamide and terminal alkene functional groups. This method is useful for the stereoselective synthesis of alkylamine derivatives containing multiple chiral centers.}, number={13}, journal={Organic Letters}, author={McCall, W. Stephen and Comins, Daniel L.}, year={2009}, month={Jun} }
 @article{mccall_grillo_comins_2008, title={<i>N</i>-Acyldihydropyridones as Synthetic Intermediates. A Stereoselective Synthesis of Acyclic Amino Alcohols Containing Multiple Chiral Centers}, DOI={10.1021/jo802029y}, abstractNote={Various multisubstituted piperidines containing a phenyl group at C-2 can be opened regio- and stereoselectively with cyanogen bromide. The ring-opened products contain useful cyanamide and benzylic bromide functional groups. The benzyl bromide can be cleanly reduced, or substituted with various nucleophiles via an S(N)2 process to add additional heteroatoms stereoselectively. This methodology is useful for the stereoselective synthesis of uniquely substituted alkylamine derivatives containing multiple chiral centers and various functionality. Diastereomerically pure amino alcohols containing three to five contiguous stereocenters were prepared using this strategy.}, number={24}, journal={The Journal of Organic Chemistry}, author={McCall, W. Stephen and Grillo, Teresa Abad and Comins, Daniel L.}, year={2008}, month={Nov} }