Works (3)

Updated: July 5th, 2023 15:50

2010 journal article

Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats

RETROVIROLOGY, 7.

By: K. Howard n, S. Reckling n, E. Egan n & G. Dean n

TL;DR: The results indicate that mucosal immune pathogenesis could be used as a rapid indicator of vaccine success or failure when combined with a physiologically relevant low dose mucosal challenge. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

In vivo depletion of CD4(+)CD25(hi) regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

VIROLOGY, 403(2), 163–172.

By: S. Mikkelsen n, S. Reckling n, E. Egan n & G. Dean n

author keywords: Feline immunodeficiency virus; HIV-1; Lentivirus; Regulatory T cell; Immunosuppression; Monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Viral / blood; CD4 Antigens / analysis; Cat Diseases / immunology; Cat Diseases / virology; Cats; Female; Immunodeficiency Virus, Feline / immunology; Interleukin-2 Receptor alpha Subunit / analysis; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Depletion; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
TL;DR: It is proposed that short-term in vivo Treg cell depletion during chronic HIV-1 infection could provide a window of opportunity for therapeutic vaccination in individuals with controlled viral replication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Safety and Immunogenicity of the Mycobacterium tuberculosis Delta lysA Delta panCD Vaccine in Domestic Cats Infected with Feline Immunodeficiency Virus

CLINICAL AND VACCINE IMMUNOLOGY, 16(3), 427–429.

By: D. Zimmerman*, W. Waters*, K. Lyashchenko*, B. Nonnecke*, D. Armstrong*, W. Jacobs n, M. Larsen n, E. Egan*, G. Dean*

MeSH headings : Animals; Antibodies, Bacterial / blood; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Hypersensitivity, Delayed; Tuberculosis Vaccines / adverse effects; Tuberculosis Vaccines / immunology
TL;DR: Feline immunodeficiency virus (FIV)-positive and FIV-negative cats received 2 × 106 CFU Mycobacterium tuberculosis ΔlysA ΔpanCD intramuscularly and elicited antibody responses, albeit at lower levels in Fiv-positive cats than in FIV -negative cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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