Erin A. Egan

Works (3)

Updated: April 25th, 2025 19:47

2010 article

Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats

Howard, K. E., Reckling, S. K., Egan, E. A., & Dean, G. A. (2010, January 19). Retrovirology.

By: K. Howard n, S. Reckling n, E. Egan n & G. Dean n

MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cat Diseases / immunology; Cat Diseases / virology; Cats; Cytokines / metabolism; Female; Immunodeficiency Virus, Feline / pathogenicity; Intestinal Mucosa / immunology; Killer Cells, Natural / immunology; Lentivirus Infections / pathology; Lentivirus Infections / veterinary; Lentivirus Infections / virology; Vagina / virology; Viral Load; Viremia
topics (OpenAlex): HIV Research and Treatment; Herpesvirus Infections and Treatments; Virology and Viral Diseases
TL;DR: The results indicate that mucosal immune pathogenesis could be used as a rapid indicator of vaccine success or failure when combined with a physiologically relevant low dose mucosal challenge. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 article

In vivo depletion of CD4+CD25hi regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

Mikkelsen, S. R., Reckling, S. K., Egan, E. A., & Dean, G. A. (2010, May 17). Virology.

By: S. Mikkelsen n, S. Reckling n, E. Egan n & G. Dean n

author keywords: Feline immunodeficiency virus; HIV-1; Lentivirus; Regulatory T cell; Immunosuppression; Monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Viral / blood; CD4 Antigens / analysis; Cat Diseases / immunology; Cat Diseases / virology; Cats; Female; Immunodeficiency Virus, Feline / immunology; Interleukin-2 Receptor alpha Subunit / analysis; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Depletion; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
topics (OpenAlex): HIV Research and Treatment; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: It is proposed that short-term in vivo Treg cell depletion during chronic HIV-1 infection could provide a window of opportunity for therapeutic vaccination in individuals with controlled viral replication. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Safety and Immunogenicity of the Mycobacterium tuberculosis Δ lysA Δ panCD Vaccine in Domestic Cats Infected with Feline Immunodeficiency Virus

Zimmerman, D. M., Waters, W. R., Lyashchenko, K. P., Nonnecke, B. J., Armstrong, D. L., Jacobs, W. R., … Dean, G. A. (2009, January 15). Clinical and Vaccine Immunology.

By: D. Zimmerman *, W. Waters *, K. Lyashchenko *, B. Nonnecke*, D. Armstrong*, W. Jacobs *, M. Larsen *, E. Egan*, G. Dean*

MeSH headings : Animals; Antibodies, Bacterial / blood; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Hypersensitivity, Delayed; Tuberculosis Vaccines / adverse effects; Tuberculosis Vaccines / immunology
topics (OpenAlex): Tuberculosis Research and Epidemiology; vaccines and immunoinformatics approaches; Mycobacterium research and diagnosis
TL;DR: Feline immunodeficiency virus (FIV)-positive and FIV-negative cats received 2 × 106 CFU Mycobacterium tuberculosis ΔlysA ΔpanCD intramuscularly and elicited antibody responses, albeit at lower levels in Fiv-positive cats than in FIV -negative cats. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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