Works (2)
Updated: July 5th, 2023 15:50
2010 journal article
Characterization of side population cells in human malignant mesothelioma cell lines
LUNG CANCER, 70(2), 146–151.
author keywords: Mesothelioma; Side population; Cancer stem cell; Hoechst 33342; Tumorigenicity; Flow cytometry
MeSH headings : Animals; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cisplatin / pharmacology; Feasibility Studies; Flow Cytometry; Gene Expression Regulation, Developmental; Humans; Mesothelioma / diagnosis; Mesothelioma / drug therapy; Mesothelioma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells / drug effects; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Side-Population Cells / drug effects; Side-Population Cells / metabolism; Side-Population Cells / pathology
TL;DR:
The data indicated that SP assay may not be appropriate for enriching putative CSCs in HMM cell lines, and thus warrants the development of a novel tool for mesothelial CSC study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
CANCER LETTERS, 278(1), 49–55.
author keywords: Malignant mesothelioma; Insulin-like growth factor 1 receptor; AG1024; Cisplatin; Chemoresistance
MeSH headings : Antineoplastic Agents / therapeutic use; Apoptosis / drug effects; Cell Division / drug effects; Cell Line, Tumor / drug effects; Cisplatin / therapeutic use; Humans; Mesothelioma / drug therapy; Pleural Neoplasms / drug therapy; Receptor, IGF Type 1 / antagonists & inhibitors; Signal Transduction / drug effects; Tyrphostins / therapeutic use
TL;DR:
This study supports the conjecture that inhibition of the IGF-1R pathway may be a useful target for reducing toxicity and alleviating chemoresistance to traditional anticancer drugs in HMM patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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