M. B. Sayer

Works (1)

Updated: July 5th, 2023 15:49

2009 journal article

Acute Effect of Pimobendan and Furosemide on the Circulating Renin-Angiotensin-Aldosterone System in Healthy Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(5), 1003–1006.

By: M. Sayer n, C. Atkins n, Y. Fujii n, A. Adams n, T. DeFrancesco n  & B. Keene n

author keywords: Furosemide; Heart failure; Inodilator; Pimobendan; Renin-angiotensin-aldosterone system
MeSH headings : Aldosterone / urine; Animals; Blood Urea Nitrogen; Chlorides / blood; Cross-Over Studies; Dogs / blood; Dogs / urine; Female; Furosemide / pharmacology; Male; Phosphorus / blood; Potassium / blood; Pyridazines / pharmacology; Renin-Angiotensin System / drug effects; Sodium / blood; Sodium Potassium Chloride Symporter Inhibitors / pharmacology; Vasodilator Agents / pharmacology
TL;DR: It is suggested that furosemide therapy, with or without pimobendan, should be accompanied by RAAS suppressive therapy, and short-term administration of high-dose pimobendedan, does not activate the RAAS in healthy dogs. (via Semantic Scholar)
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Added: August 6, 2018

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