I. Caballero

Works (1)

Updated: July 5th, 2023 15:49

2009 journal article

EVALUATION OF THE SERRATIA MARCESCENS NUCLEASE (NucA) AS A TRANSGENIC CELL ABLATION SYSTEM IN PORCINE

ANIMAL BIOTECHNOLOGY, 20(4), 177–185.

By: I. Caballero n & J. Piedrahita n 

author keywords: Ablation; DTA; Fibroblasts; NucA; Porcine
MeSH headings : Animals; Cell Separation / methods; Cells, Cultured; Electroporation / methods; Endodeoxyribonucleases / analysis; Endodeoxyribonucleases / genetics; Endodeoxyribonucleases / metabolism; Endoribonucleases / analysis; Endoribonucleases / genetics; Endoribonucleases / metabolism; Fibroblasts / metabolism; Gene Expression; Gene Transfer Techniques; Rabbits; Serratia / enzymology; Swine
topics (OpenAlex): CRISPR and Genetic Engineering; Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects
TL;DR: Gene expression analysis of surviving colonies indicated that survival is related to low or absent expression of the toxic genes, and results indicate that the NucA gene, while capable of mammalian cell ablation, is less efficient than DTA. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.