Works (7)
Updated: July 5th, 2023 15:49
2011 journal article
Evaluation of the cyclooxygenase selectivity of robenacoxib and its effect on recovery of ischemia-injured jejunal mucosa in horses
American Journal of Veterinary Research, 72(2), 226–232.
Contributors: n, A. Bhatnagar n, S. Bowman n, C. Howard n, N. Morris n, D. Skorich n, C. Redding n, A. Blikslager n
MeSH headings : Animals; Cyclooxygenase 1 / metabolism; Cyclooxygenase Inhibitors / pharmacology; Cyclooxygenase Inhibitors / therapeutic use; Diphenylamine / analogs & derivatives; Diphenylamine / pharmacology; Diphenylamine / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Intestinal Diseases / drug therapy; Intestinal Diseases / pathology; Intestinal Diseases / veterinary; Ischemia / pathology; Ischemia / veterinary; Jejunum / pathology; Phenylacetates / pharmacology; Phenylacetates / therapeutic use
TL;DR:
Robenacoxib selectively inhibited COX-2 and allowed recovery of barrier function in ischemia-injured equine jejunal tissue in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
The effect of nonsteroidal anti-inflammatory drugs on the equine intestine
Equine Veterinary Journal, 43(SUPPL.39), 140–144.
Contributors: * & A. Blikslager n
author keywords: horse; NSAID; intestine; injury
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Gastrointestinal Diseases / chemically induced; Gastrointestinal Diseases / veterinary; Horse Diseases / chemically induced; Horses; Intestines / drug effects
TL;DR:
Experimental evidence suggests that those NSAIDs with cyclooxygenase independent anti-inflammatory effects or a COX-2 selective mode of action may offer significant advantages over traditional NSAIDs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo
Equine Veterinary Journal, 43(SUPPL.39), 106–111.
Contributors: n, A. Bhatnagar n, S. Bowman n, N. Morris n, D. Skorich n, C. Redding n, A. Blikslager n
TL;DR:
Flunixin meglumine and AHI-805 inhibit recovery of barrier function in ischaemic-injured equine jejunum in vitro through inhibition of the COX enzymes.
(via Semantic Scholar)
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Demographic characteristics of horses donated to the North Carolina State University Equine Health Center, 1996–2008
Journal of the American Veterinary Medical Association, 236(12), 1334–1337.
Contributors: S. Bowman n, * & A. Blikslager*
MeSH headings : Animals; Cohort Studies; Demography; Education, Veterinary; Female; Horse Diseases / epidemiology; Horses; Male; North Carolina; Retrospective Studies; Universities
TL;DR:
The most common reason given for unwanted horses offered for donation during 2007 and 2008 was musculoskeletal disease, with degenerative joint disease, lameness of undetermined cause, laminitis, and navicular disease being the most common musculosity conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
The pharmacokinetics and in vitro cyclooxygenase selectivity of deracoxib in horses
Journal of Veterinary Pharmacology and Therapeutics, 34(1), 12–16.
Contributors: J. Davis*, *, M. Papich n , A. Blikslager* & N. Campbell n
MeSH headings : Animals; Cyclooxygenase Inhibitors / blood; Cyclooxygenase Inhibitors / pharmacokinetics; Cyclooxygenase Inhibitors / pharmacology; Horses / blood; Horses / metabolism; Sulfonamides / blood; Sulfonamides / pharmacokinetics; Sulfonamides / pharmacology
TL;DR:
It is shown that deracoxib is absorbed in the horse after oral administration, and may offer a useful alternative for anti-inflammatory treatment of various conditions in the dog and horse.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2009 journal article
Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses
American Journal of Veterinary Research, 70(10), 1259–1268.
Contributors: V. Cook n, J. Jones Shults n, M. McDowell n, N. Campbell n, J. Davis n, n, A. Blikslager n
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Clonixin / adverse effects; Clonixin / analogs & derivatives; Female; Gene Expression Regulation, Enzymologic / drug effects; Horse Diseases / chemically induced; Horse Diseases / drug therapy; Horses; Intestinal Diseases / chemically induced; Intestinal Diseases / veterinary; Ischemia / chemically induced; Jejunum / drug effects; Lidocaine / therapeutic use; Male; Prostaglandin-Endoperoxide Synthases / genetics; Prostaglandin-Endoperoxide Synthases / metabolism
TL;DR:
In horses with ischemia-injured jejunum, lidocaine administered IV reduced plasma prostaglandin E(2) metabolite concentration and mucosal COX-2 expression and coadministration of lidocane with flunixin ameliorated the flunxin-induced increase in mucosal neutrophil counts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
COMPARISON OF FLAT-PANEL DIGITAL TO CONVENTIONAL FILM-SCREEN RADIOGRAPHY IN DETECTION OF EXPERIMENTALLY CREATED LESIONS OF THE EQUINE THIRD METACARPAL BONE
VETERINARY RADIOLOGY & ULTRASOUND, 50(6), 577–583.
author keywords: digital radiography; equine metacarpus; film-screen radiography; lesion detection
MeSH headings : Animals; Bone Diseases / diagnostic imaging; Bone Diseases / veterinary; Euthanasia, Animal; Horse Diseases / diagnostic imaging; Horses; Metacarpal Bones / diagnostic imaging; Models, Animal; ROC Curve; Radiographic Image Enhancement / methods; Radiographic Image Enhancement / standards; Tomography, X-Ray Computed / standards; Tomography, X-Ray Computed / veterinary; X-Ray Film / veterinary
TL;DR:
It was concluded that the digital radiographic system was comparable to the film-screen system for detection of subtle lesions of the equine third metacarpal bone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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