@article{dalal_lewis_tietz_brown_brown_palme_muday_sederoff_2016, title={ROSY1, a novel regulator of gravitropic response is a stigmasterol binding protein}, volume={196-197}, ISSN={["1618-1328"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84962208471&partnerID=MN8TOARS}, DOI={10.1016/j.jplph.2016.03.011}, abstractNote={The gravitropic bending in plant roots is caused by asymmetric cell elongation. This requires an asymmetric increase in cell surface and therefore plasma membrane components such as lipids, sterols, and membrane proteins. We have identified an early gravity-regulated protein in Arabidopsis thaliana root apices that binds stigmasterol and phosphoethanolamines. This root-specific protein interacts with the membrane transport protein synaptotagmin-1 and was therefore named InteractoR Of SYnaptotagmin1 (ROSY1). While interactions between ML-domain proteins with membrane transport proteins and their impact have been reported from animal cell systems, this is the first report of such an interaction in a plant system. Homozygous mutants of ROSY1 exhibit decreased basipetal auxin transport, a faster root gravitropic response, and an increase in salt stress tolerance. Our results suggest that ROSY1 plays a role in root gravitropism, possibly by facilitating membrane trafficking and asymmetric cell elongation via its interaction with synaptotagmin-1.}, journal={JOURNAL OF PLANT PHYSIOLOGY}, author={Dalal, Jyoti and Lewis, Daniel R. and Tietz, Olaf and Brown, Erica M. and Brown, Christopher S. and Palme, Klaus and Muday, Gloria K. and Sederoff, Heike W.}, year={2016}, month={Jun}, pages={28–40} }
 @article{khodakovskaya_sword_wu_perera_boss_brown_sederoff_2010, title={Increasing inositol (1,4,5)-trisphosphate metabolism affects drought tolerance, carbohydrate metabolism and phosphate-sensitive biomass increases in tomato}, volume={8}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-73949085190&partnerID=MN8TOARS}, DOI={10.1111/j.1467-7652.2009.00472.x}, abstractNote={Inositol-(1,4,5)-trisphosphate (InsP(3)) is a second messenger in plants that increases in response to many stimuli. The metabolic consequences of this signalling pathway are not known. We reduced the basal level of InsP(3) in tomato (Solanum lycopersicum cv. Micro-Tom) by expressing the human type I inositol polyphosphate 5-phosphatase (InsP 5-ptase) gene. Transgenic lines producing InsP 5-ptase protein had between 15% and 30% of the basal InsP(3) level of control plants. This increased hydrolysis of InsP(3) caused dramatic increases in drought tolerance, vegetative biomass and lycopene and hexose concentrations in the fruits. Transcript profiling of root, leaf and fruit tissues identified a small group of genes, including a cell-wall invertase inhibitor gene, that were differentially regulated in all tissues of the InsP 5-ptase expressing plants. Significant differences were found in the amounts of carbohydrates and organic phosphate in these plants. Plants with increased hydrolysis of InsP(3) in the cytosol also showed increased net CO(2)-fixation and sucrose export into sink tissue and storage of hexoses in the source leaves. The increase in biomass was dependent on the supply of inorganic phosphate in the nutrient medium. Uptake and storage of phosphate was increased in the transgene expressing lines. This suggests that in tomato, increased flux through the inositol phosphate pathway uncoupled phosphate sensing from phosphate metabolism. Altering the second messenger, InsP(3), revealed multiple coordinated changes in development and metabolism in tomato that have potential for crop improvement.}, number={2}, journal={Plant Biotechnology Journal}, author={Khodakovskaya, M. and Sword, C. and Wu, Q. and Perera, I. Y. and Boss, W. F. and Brown, C. S. and Sederoff, Heike}, year={2010}, pages={170–183} }
 @article{kimbrough_salinas-mondragon_boss_brown_sederoff_2004, title={The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root Apex}, volume={136}, ISSN={["1532-2548"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-16544389872&partnerID=MN8TOARS}, DOI={10.1104/pp.104.044594}, abstractNote={Abstract}, number={1}, journal={PLANT PHYSIOLOGY}, author={Kimbrough, JM and Salinas-Mondragon, R and Boss, WE and Brown, CS and Sederoff, HW}, year={2004}, month={Sep}, pages={2790–2805} }
 @article{klymchuk_kordyum_vorobyova_chapman_brown_2003, title={Changes in vacuolation in the root apex cells of soybean seedlings in microgravity}, volume={31}, DOI={10.1016/S0273.1177(03)00256-4}, abstractNote={Changes in the vacuolation in root apex cells of soybean (Glycine max L. [Merr.]) seedlings grown in microgravity were investigated. Spaceflight and ground control seedlings were grown in the absence or presence of KMnO4 (to remove ethylene) for 6 days. After landing, in order to study of cell ultrastructure and subcellular free calcium ion distribution, seedling root apices were fixed in 2.5% (w/v) glutaraldehyde in 0.1 M cacodylate buffer and 2% (w/v) glutaraldehyde, 2.5% (w/v) formaldehyde, 2% (w/v) potassium antimonate K[Sb(OH)6] in 0.1 M K2HPO4 buffer with an osmolarity (calculated theoretically) of 0.45 and 1.26 osmol. The concentrations of ethylene in all spaceflight canisters were significantly higher than in the ground control canisters. Seedling growth was reduced in the spaceflight-exposed plants. Additionally, the spaceflight-exposed plants exhibited progressive vacuolation in the root apex cells, particularly in the columella cells, to a greater degree than the ground controls. Plasmolysis was observed in columella cells of spaceflight roots fixed in solutions with relatively high osmolarity (1.26 osmol). The appearance of plasmolysis permitted the evaluation of the water status of cells. The water potential of the spaceflight cells was higher than the surrounding fixative solution. A decrease in osmotic potential and/or an increase in turgor potential may have induced increases in cell water potential. However, the plasmolysed (i.e. non-turgid) cells implied that increases in water potential were accompanied with a decrease in osmotic potential. In such cells changes in vacuolation may have been involved to maintain turgor pressure or may have been a result of intensification of other vacuolar functions like digestion and storage.}, number={10}, journal={Space life sciences: Gravity-related processes in plants (Advances in space research ; 31)}, publisher={Oxford: Published for the Committee on Space Research [by] Pergamon}, author={Klymchuk, D. O. and Kordyum, E. L. and Vorobyova, T. V. and Chapman, D. K. and Brown, C. S.}, editor={J. Z. Kiss and Kern, V. D.Editors}, year={2003}, pages={2283–2288} }
 @article{brown_young_pharr_1985, title={Rootstock and scion effects on carbon partitioning in apple leaves}, volume={110}, number={5}, journal={Journal of the American Society for Horticultural Science}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1985}, pages={701} }
 @article{brown_young_pharr_1985, title={Rootstock and scion effects on the seasonal distribution of dry weight and carbohydrates in young apple trees}, volume={110}, number={5}, journal={Journal of the American Society for Horticultural Science}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1985}, pages={696} }
 @article{brown_young_pharr_1983, title={An enzymatic assay for sorbitol in apple organs}, volume={18}, number={4}, journal={HortScience}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1983}, pages={469} }