@article{dalal_lewis_tietz_brown_brown_palme_muday_sederoff_2016, title={ROSY1, a novel regulator of gravitropic response is a stigmasterol binding protein}, volume={196-197}, ISSN={["1618-1328"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84962208471&partnerID=MN8TOARS}, DOI={10.1016/j.jplph.2016.03.011}, abstractNote={The gravitropic bending in plant roots is caused by asymmetric cell elongation. This requires an asymmetric increase in cell surface and therefore plasma membrane components such as lipids, sterols, and membrane proteins. We have identified an early gravity-regulated protein in Arabidopsis thaliana root apices that binds stigmasterol and phosphoethanolamines. This root-specific protein interacts with the membrane transport protein synaptotagmin-1 and was therefore named InteractoR Of SYnaptotagmin1 (ROSY1). While interactions between ML-domain proteins with membrane transport proteins and their impact have been reported from animal cell systems, this is the first report of such an interaction in a plant system. Homozygous mutants of ROSY1 exhibit decreased basipetal auxin transport, a faster root gravitropic response, and an increase in salt stress tolerance. Our results suggest that ROSY1 plays a role in root gravitropism, possibly by facilitating membrane trafficking and asymmetric cell elongation via its interaction with synaptotagmin-1.}, journal={JOURNAL OF PLANT PHYSIOLOGY}, author={Dalal, Jyoti and Lewis, Daniel R. and Tietz, Olaf and Brown, Erica M. and Brown, Christopher S. and Palme, Klaus and Muday, Gloria K. and Sederoff, Heike W.}, year={2016}, month={Jun}, pages={28–40} }
 @article{khodakovskaya_sword_wu_perera_boss_brown_sederoff_2010, title={Increasing inositol (1,4,5)-trisphosphate metabolism affects drought tolerance, carbohydrate metabolism and phosphate-sensitive biomass increases in tomato}, volume={8}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-73949085190&partnerID=MN8TOARS}, DOI={10.1111/j.1467-7652.2009.00472.x}, abstractNote={Summary Inositol‐(1,4,5)‐trisphosphate (InsP 3 ) is a second messenger in plants that increases in response to many stimuli. The metabolic consequences of this signalling pathway are not known. We reduced the basal level of InsP 3 in tomato ( Solanum lycopersicum cv. Micro‐Tom) by expressing the human type I inositol polyphosphate 5‐phosphatase (InsP 5‐ptase) gene. Transgenic lines producing InsP 5‐ptase protein had between 15% and 30% of the basal InsP 3 level of control plants. This increased hydrolysis of InsP 3 caused dramatic increases in drought tolerance, vegetative biomass and lycopene and hexose concentrations in the fruits. Transcript profiling of root, leaf and fruit tissues identified a small group of genes, including a cell‐wall invertase inhibitor gene, that were differentially regulated in all tissues of the InsP 5‐ptase expressing plants. Significant differences were found in the amounts of carbohydrates and organic phosphate in these plants. Plants with increased hydrolysis of InsP 3 in the cytosol also showed increased net CO 2 ‐fixation and sucrose export into sink tissue and storage of hexoses in the source leaves. The increase in biomass was dependent on the supply of inorganic phosphate in the nutrient medium. Uptake and storage of phosphate was increased in the transgene expressing lines. This suggests that in tomato, increased flux through the inositol phosphate pathway uncoupled phosphate sensing from phosphate metabolism. Altering the second messenger, InsP 3 , revealed multiple coordinated changes in development and metabolism in tomato that have potential for crop improvement.}, number={2}, journal={Plant Biotechnology Journal}, author={Khodakovskaya, M. and Sword, C. and Wu, Q. and Perera, I. Y. and Boss, W. F. and Brown, C. S. and Sederoff, Heike}, year={2010}, pages={170–183} }
 @article{kimbrough_salinas-mondragon_boss_brown_sederoff_2004, title={The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root Apex}, volume={136}, ISSN={["1532-2548"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-16544389872&partnerID=MN8TOARS}, DOI={10.1104/pp.104.044594}, abstractNote={Abstract Plant root growth is affected by both gravity and mechanical stimulation (Massa GD, Gilroy S [2003] Plant J 33: 435–445). A coordinated response to both stimuli requires specific and common elements. To delineate the transcriptional response mechanisms, we carried out whole-genome microarray analysis of Arabidopsis root apices after gravity stimulation (reorientation) and mechanical stimulation and monitored transcript levels of 22,744 genes in a time course during the first hour after either stimulus. Rapid, transient changes in the relative abundance of specific transcripts occurred in response to gravity or mechanical stimulation, and these transcript level changes reveal clusters of coordinated events. Transcriptional regulation occurs in the root apices within less than 2 min after either stimulus. We identified genes responding specifically to each stimulus as well as transcripts regulated in both signal transduction pathways. Several unknown genes were specifically induced only during gravitropic stimulation (gravity induced genes). We also analyzed the network of transcriptional regulation during the early stages of gravitropism and mechanical stimulation.}, number={1}, journal={PLANT PHYSIOLOGY}, author={Kimbrough, JM and Salinas-Mondragon, R and Boss, WE and Brown, CS and Sederoff, HW}, year={2004}, month={Sep}, pages={2790–2805} }
 @article{klymchuk_kordyum_vorobyova_chapman_brown_2003, title={Changes in vacuolation in the root apex cells of soybean seedlings in microgravity}, volume={31}, DOI={10.1016/S0273.1177(03)00256-4}, number={10}, journal={Space life sciences: Gravity-related processes in plants (Advances in space research ; 31)}, publisher={Oxford: Published for the Committee on Space Research [by] Pergamon}, author={Klymchuk, D. O. and Kordyum, E. L. and Vorobyova, T. V. and Chapman, D. K. and Brown, C. S.}, editor={J. Z. Kiss and Kern, V. D.Editors}, year={2003}, pages={2283–2288} }
 @article{brown_young_pharr_1985, title={Rootstock and scion effects on carbon partitioning in apple leaves}, volume={110}, number={5}, journal={Journal of the American Society for Horticultural Science}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1985}, pages={701} }
 @article{brown_young_pharr_1985, title={Rootstock and scion effects on the seasonal distribution of dry weight and carbohydrates in young apple trees}, volume={110}, number={5}, journal={Journal of the American Society for Horticultural Science}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1985}, pages={696} }
 @article{brown_young_pharr_1983, title={An enzymatic assay for sorbitol in apple organs}, volume={18}, number={4}, journal={HortScience}, author={Brown, C. S. and Young, E. and Pharr, D. M.}, year={1983}, pages={469} }