Sanjay Chanda

Works (3)

Updated: July 5th, 2023 16:02

2002 journal article

17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice

TOXICOLOGICAL SCIENCES, 69(1), 42–48.

By: K. Porter n, S. Chanda, H. Wang, K. Gaido, R. Smart  & C. Robinette

author keywords: mirex; skin; 17 beta-estradiol; tumor promotion; endocrine
MeSH headings : Animals; Carcinogens / toxicity; Cell Line; Chlordecone / toxicity; Drug Implants; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Genes, Reporter / drug effects; Insecticides / toxicity; Luciferases / biosynthesis; Male; Mice; Mirex / toxicity; Orchiectomy; Ovariectomy; Radioimmunoassay; Sex Characteristics
TL;DR: Collectively, these studies indicate that E2 is a major ovarian hormone responsible for mirex tumor promotion sensitivity in female mice. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

17 beta-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 278(2), E202–E210.

By: S. Chanda*, C. Robinette n, J. Couse* & R. Smart* 

author keywords: skin; hair growth; hormones; androgens
MeSH headings : Administration, Topical; Animals; Blotting, Northern; Dose-Response Relationship, Drug; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / administration & dosage; Estrogen Antagonists / pharmacology; Estrogen Receptor alpha; Female; Fulvestrant; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / physiology; Immunohistochemistry; Mice; Ovariectomy; RNA, Messenger / analysis; Receptors, Estrogen / drug effects; Receptors, Estrogen / genetics; Receptors, Estrogen / physiology; Skin / drug effects; Skin / metabolism
TL;DR: Findings implicate a skin-specific ER-alpha pathway in the regulation of the hair follicle cycle and indicate the direct rather than secondary systemic nature of their effects. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 article

Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice

Smart, R. C., Oh, H. S., Chanda, S., & Robinette, C. L. (1999, December). JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, Vol. 4, pp. 285–289.

By: R. Smart n , H. Oh n, S. Chanda n & C. Robinette n

author keywords: alopecia; dermal papilla; estrogen receptor; hair follicle
MeSH headings : Administration, Topical; Animals; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Estrogen Antagonists / administration & dosage; Female; Fulvestrant; Hair / drug effects; Hair / growth & development; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL
TL;DR: The results demonstrate that (i) the route of administration of 17-beta-estradiol is critical for its ability to block hair growth, and (ii) C57BL/6 and C3H mice, two commonly employed mouse strains for hair growth studies, responded to 17- beta-ESTradiol and ICI 182 780 in a manner similar to that described in CD-1 mice. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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