Thomas E. Eling

Works (1)

Updated: July 5th, 2023 16:00

2001 journal article

Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter - Basal transcription is mediated by Sp1 and Sp3

JOURNAL OF BIOLOGICAL CHEMISTRY, 276(36), 33384–33392.

By: S. Baek *, J. Horowitz n & T. Eling*

MeSH headings : Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Base Sequence; Binding Sites; COUP Transcription Factor I; Cell Nucleus / metabolism; Chromatin / metabolism; Cloning, Molecular; Cytokines / genetics; Cytokines / metabolism; DNA-Binding Proteins / metabolism; Gene Deletion; Genes, Reporter; Glutathione Transferase / metabolism; Growth Differentiation Factor 15; Humans; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids / metabolism; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins / metabolism; Recombinant Proteins / metabolism; Sequence Homology, Nucleic Acid; Sp1 Transcription Factor / metabolism; Sp3 Transcription Factor; Transcription Factors / metabolism; Transcription, Genetic; Transfection
TL;DR: The results suggest that the level of expression of the NAG-1 gene will depend on the availability of Sp proteins and on co-factors such as chicken ovalbumin upstream promoter-transcription factor 1. (via Semantic Scholar)
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Added: August 6, 2018

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