Works (1)
Updated: July 5th, 2023 15:49
2009 journal article
Vesicle-associated Membrane Protein (VAMP) Cleavage by a New Metalloprotease from the Brazilian Scorpion Tityus serrulatus
JOURNAL OF BIOLOGICAL CHEMISTRY, 285(10), 7405–7416.
MeSH headings : Amino Acid Sequence; Animals; Guinea Pigs; Immunohistochemistry; Metalloproteases / metabolism; Metalloproteases / ultrastructure; Models, Molecular; Molecular Sequence Data; Pancreas, Exocrine / anatomy & histology; Pancreas, Exocrine / metabolism; Protein Conformation; Protein Isoforms / metabolism; R-SNARE Proteins / metabolism; R-SNARE Proteins / ultrastructure; SNARE Proteins / metabolism; Scorpion Venoms / enzymology; Scorpions / enzymology; Secretory Vesicles / chemistry; Secretory Vesicles / ultrastructure
TL;DR:
Evidence is presented that venom from the Brazilian scorpion Tityus serrulatus and a purified fraction selectively cleave essential SNARE proteins within exocrine pancreatic tissue and the unique cleavages of VAMP2 and VAMP8 may be linked to pancreatitis that develops following scorpion envenomation.
(via Semantic Scholar)
open access via www.jbc.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.