@article{wolfe_libby_al-awar_foti_comins_2010, title={Asymmetric Synthesis of All the Known Phlegmarine Alkaloids}, volume={75}, ISSN={["0022-3263"]}, DOI={10.1021/jo1019688}, abstractNote={The asymmetric synthesis of all four of the known natural phlegmarines and one synthetic derivative has been accomplished in 19-22 steps from 4-methoxy-3-(triisopropylsilyl)pyridine. Chiral N-acylpyridinium salt chemistry was used twice to set the stereocenters at the C-9 and C-2' positions of the phlegmarine skeleton. Key reactions include the use of a mixed Grignard reagent for the second N-acylpyridinium salt addition, zinc/acetic acid reduction of a complex dihydropyridone, and a von Braun cyanogen bromide N-demethylation of a late intermediate. These syntheses confirmed the absolute stereochemistry of all of the known phlegmarines.}, number={24}, journal={JOURNAL OF ORGANIC CHEMISTRY}, author={Wolfe, Bradley H. and Libby, Adam H. and Al-awar, Rima S. and Foti, Christopher J. and Comins, Daniel L.}, year={2010}, month={Dec}, pages={8564–8570} } @misc{comins_libby_al-awar_foti_1999, title={Asymmetric synthesis of the Lycopodium alkaloid, N-a-acetyl-N-b-methylphlegmarine}, volume={64}, ISSN={["0022-3263"]}, DOI={10.1021/jo990192k}, abstractNote={ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTAsymmetric Synthesis of the Lycopodium Alkaloid, Na-Acetyl-Nb-methylphlegmarineDaniel L. Comins, Adam H. Libby, Rima S. Al-awar, and Christopher J. FotiView Author Information Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695-8204 Cite this: J. Org. Chem. 1999, 64, 7, 2184–2185Publication Date (Web):March 6, 1999Publication History Received2 February 1999Published online6 March 1999Published inissue 1 April 1999https://doi.org/10.1021/jo990192kCopyright © 1999 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1204Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (151 KB) Get e-AlertsSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Enantioselective synthesis,Hydrocarbons,Organic compounds,Redox reactions,Stereochemistry Get e-Alerts}, number={7}, journal={JOURNAL OF ORGANIC CHEMISTRY}, author={Comins, DL and Libby, AH and Al-awar, RS and Foti, CJ}, year={1999}, month={Apr}, pages={2184–2185} } @article{comins_foti_libby_1998, title={Model studies toward the synthesis of N alpha-acetyl-N beta- methylphlegmarine: Addition of cyclohexylmethyl organometallics to 1-acylpyridinium salts}, volume={48}, DOI={10.3987/com-98-8148}, number={7}, journal={Heterocycles}, author={Comins, D. L. and Foti, C. J. and Libby, A. H.}, year={1998}, pages={1313–1317} }