2010 journal article

Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications for Dermal Risk Assessment Studies


By: J. Riviere n, J. Brooks*, J. Yeatts* & E. Koivisto*

MeSH headings : Administration, Cutaneous; Alkanesulfonic Acids / pharmacology; Animals; Complex Mixtures / chemistry; Complex Mixtures / pharmacokinetics; Drug Interactions; Female; Membranes, Artificial; Organic Chemicals / pharmacokinetics; Risk Assessment; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Skin Absorption / physiology; Sodium Dodecyl Sulfate / pharmacology; Solubility; Surface-Active Agents / pharmacology; Surgical Flaps; Swine; Water / chemistry
TL;DR: The inert three-fiber MCF array predicted absorptive fluxes seen in the ex vivo IPPSF, suggesting lack of any biological effects of the surfactants on skin. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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