Works (6)

Updated: July 5th, 2023 16:02

2002 journal article

Suppressor cell activity of ovine caruncular and intercaruncular tissues during the placentation period

THERIOGENOLOGY, 58(6), 1097–1109.

By: . Miles*, P. Beetham & E. Segerson*

author keywords: ovine; immunosuppression; uterus; lymphocytes
MeSH headings : Animals; Antibodies / pharmacology; Coculture Techniques; Endometrium / cytology; Endometrium / immunology; Female; Lymphocyte Activation / drug effects; Lymphocytes / immunology; Phytohemagglutinins / pharmacology; Placentation; Pregnancy; Swine; T-Lymphocytes, Regulatory / physiology; Transforming Growth Factor beta / immunology; Transforming Growth Factor beta / physiology
TL;DR: A temporal pattern in suppressor activity for unfractionated endometrial cells during pregnancy is observed and the suppressor cells may provide immunological protection to the fetoplacental unit by suppressing specific lymphocyte responses directed toward conceptus tissues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Ovine endometrial cells fail to lyse K-562 target cells: a preliminary investigation

Theriogenology, 51(8), 1431–1440.

By: A. Ireland* & E. Segerson*

MeSH headings : Animals; Chromium Radioisotopes; Coculture Techniques; Corpus Luteum / physiology; Cytotoxicity, Immunologic; Endometrium / cytology; Endometrium / immunology; Female; Killer Cells, Lymphokine-Activated / immunology; Killer Cells, Natural / immunology; Pregnancy; Progesterone / blood; Sheep; Tumor Cells, Cultured
TL;DR: Preliminary findings indicate that ovine endometrial cells recovered during the late luteal phase and early pregnancy failed to exhibit natural killer activity upon K-562 target cells. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Endometrial suppressor cells in beef cattle

THERIOGENOLOGY, 50(5), 779–791.

By: S. Shipp* & E. Segerson*

author keywords: T-lymphocyte; endometrium; immunosuppression; growth factor
MeSH headings : Animals; Antibodies; Cattle / immunology; Cell Division; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Endometrium / cytology; Endometrium / immunology; Female; Immune Tolerance; Leukocytes, Mononuclear / immunology; Lymphocytes / immunology; Phytohemagglutinins / pharmacology; Pregnancy; Transforming Growth Factor beta / immunology; Transforming Growth Factor beta / physiology
TL;DR: The bovine endometrium contains low- and high-density suppressor cells capable of releasing suppressor factor, which seems to be associated with TGF-beta. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Partial characterization of ovine intrauterine suppressor cells

BIOLOGY OF REPRODUCTION, 58(2), 397–406.

By: E. Segerson*, H. Li*, C. Talbott*, J. Allen* & F. Gunsett*

MeSH headings : Animals; Antigens, CD / analysis; Cell Count; Cell Size; Cells, Cultured; Coculture Techniques; Estrus / physiology; Female; Immunohistochemistry; Monocytes / immunology; Monocytes / physiology; Pregnancy; Sheep; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / physiology; Transforming Growth Factor beta / metabolism; Uterus / cytology
TL;DR: Low-density uterine cells from cyclic and pregnant ewes suppressed the proliferation of cocultured PBL and released a suppressor factor into the medium that did not exhibit TGFbeta activity, suggesting it is unlikely that the suppressor cells comprise conventional T-, B-, or NK-like lymphocyte lineages. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Estradiol-17 beta and progesterone increase ovine uterine suppressor cell activity

Journal of Animal Science, 75(10), 2778–2787.

By: E. Segerson*, H. Li* & C. Talbott*

MeSH headings : Animals; Cell Division / drug effects; Cell Division / physiology; Cells, Cultured; Coculture Techniques / veterinary; Culture Media / chemistry; DNA / metabolism; Dose-Response Relationship, Drug; Endometrium / cytology; Estradiol / pharmacology; Female; Ovariectomy / veterinary; Phytohemagglutinins / pharmacology; Progesterone / pharmacology; Regression Analysis; Sheep / metabolism; Sheep / physiology; Suppressor Factors, Immunologic / analysis; Suppressor Factors, Immunologic / metabolism; T-Lymphocytes, Regulatory / drug effects; T-Lymphocytes, Regulatory / metabolism; T-Lymphocytes, Regulatory / physiology; Thymidine / metabolism; Uterus / cytology; Uterus / drug effects; Uterus / physiology
TL;DR: It is demonstrated that reproductive steroids augment ovine uterine (UT) suppressor cell activity with varying concentrations of each steroid preparation. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Transforming growth factor-beta 2 activity is temporally associated with a porcine high-molecular-weight uterine component recovered during early pregnancy

Journal of Animal Science, 75(2), 462–468.

By: E. Segerson* & C. Talbott*

MeSH headings : Analysis of Variance; Animals; Cell Division / physiology; Chromatography, Agarose / methods; Chromatography, Agarose / veterinary; Female; Isomerism; Lymphocytes / cytology; Lymphocytes / physiology; Molecular Weight; Pregnancy; Pregnancy, Animal / blood; Pregnancy, Animal / metabolism; Pregnancy, Animal / physiology; Swine / metabolism; Swine / physiology; Transforming Growth Factor beta / analysis; Transforming Growth Factor beta / metabolism; Transforming Growth Factor beta / physiology; Uterus / chemistry; Uterus / metabolism
TL;DR: A temporal pattern of TGF-beta activity was associated with a > or = 4 MDa carrier recovered from porcine uterine luminal secretions during early pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

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