@article{haschek_berenbaum_hinton_cora_chernoff_travlos_liu_lu_law_2019, title={Pathology in Ecological Research With Implications for One Health: Session Summary}, volume={47}, ISSN={["1533-1601"]}, DOI={10.1177/0192623319880530}, abstractNote={This session explored the effects of pollutants on One Health at the ecosystem level that included microbes, insects, fish, and humans. The concept of One Health seeks to synergize medical, veterinary, and other health science disciplines to more effectively advance human and animal health. Presentations explored the interactions of pesticides, pathogens, phytochemicals, and xenobiotic biotransformation in bee colony losses critical for food security (bees have been recently listed under the 2017 US Food and Drug Administration (FDA) veterinary feed directive); the role of pathology in identifying the effects of pollutants on fish as sentinels for human health; the effects in rats of per- and polyfluoroalkyl substances (PFAS) that can persist in the environment and contaminate drinking water; harmful algal blooms and toxin production leading to animal and human disease; and the processing of environmental carcinogens by intestinal microbiota.}, number={8}, journal={TOXICOLOGIC PATHOLOGY}, author={Haschek, Wanda M. and Berenbaum, May and Hinton, David E. and Cora, Michelle and Chernoff, Neil and Travlos, Gregory and Liu, Chih-Wei and Lu, Kun and Law, Mac}, year={2019}, month={Dec}, pages={1072–1075} } @article{cora_neel_grindem_kissling_hess_2013, title={Comparison of automated versus manual neutrophil counts for the detection of cellular abnormalities in dogs receiving chemotherapy: 50 cases (May to June 2008)}, volume={242}, ISSN={["0003-1488"]}, url={https://doi.org/10.2460/javma.242.11.1539}, DOI={10.2460/javma.242.11.1539}, abstractNote={Abstract Objective —To determine the frequency of clinically relevant abnormalities missed by failure to perform a blood smear evaluation in a specific subset of dogs receiving chemotherapy and to compare automated and manual neutrophil counts in the same population Design —Retrospective case series Animals —50 dogs receiving chemotherapy with a total nucleated cell count > 4,000 nucleated cells/μL. Procedures —50 blood smears were evaluated for abnormalities that have strong potential to change the medical plan for a patient: presence of blast cells, band neutrophils, nucleated RBCs, toxic change, hemoparasites, schistocytes, and spherocytes. Automated and manual neutrophil counts were compared. Results —Blood smears from 10 (20%) patients had ≥ 1 abnormalities. Blast cells were identified on 4 (8%) blood smears, increased nucleated RBCs were identified on 5 (10%), and very mild toxic change was identified on 2 (4%). Correlation coefficient of the neutrophil counts was 0.96. Analysis revealed a slight bias between the automated and manual neutrophil counts (mean ± SD difference, −0.43 × 10 3 /μL ± 1.10 × 10 3 /μL) Conclusions and Clinical Relevance —In this series of patients, neutrophil count correlation was very good. Clinically relevant abnormalities were found on 20% of the blood smears. An automated CBC appears to be accurate for neutrophil counts, but a microscopic examination of the corresponding blood smear is still recommended; further studies are needed to determine whether the detection or frequency of these abnormalities would differ dependent on chemotherapy protocol, neoplastic disease, and decision thresholds used by the oncologist in the ordering of a CBC without a blood smear evaluation.}, number={11}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Cora, Michelle C. and Neel, Jennifer A. and Grindem, Carol B. and Kissling, Grace E. and Hess, Paul R.}, year={2013}, month={Jun}, pages={1539–1543} } @article{cora_neel_tarigo_post_barnes_2010, title={Francisella philomiragia Septicemia in a Dog}, volume={24}, ISSN={["0891-6640"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-77956640280&partnerID=MN8TOARS}, DOI={10.1111/j.1939-1676.2010.0545.x}, number={4}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Cora, M. C. and Neel, J. A. and Tarigo, J. and Post, K. and Barnes, J.}, year={2010}, pages={969–972} }