Works (5)
Updated: July 5th, 2023 16:03
2004 journal article
Failure of FIV-infected cats to control Toxoplasma gondii correlates with reduced IL2, IL6, and IL12 and elevated IL10 expression by lymph node T cells
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 98(1-2), 101–111.
author keywords: FIV; cytokine; Toxoplasma gondii
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cat Diseases / genetics; Cat Diseases / immunology; Cats; Gene Expression; Immunodeficiency Virus, Feline; Interleukin-10 / genetics; Interleukin-12 / genetics; Interleukin-2 / genetics; Interleukin-6 / genetics; Interleukins / genetics; Lentivirus Infections / complications; Lentivirus Infections / genetics; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; RNA, Messenger / genetics; RNA, Messenger / metabolism; T-Lymphocytes / immunology; Toxoplasmosis, Animal / complications; Toxoplasmosis, Animal / genetics; Toxoplasmosis, Animal / immunology
TL;DR:
Elevated IL10 may suppress a Th1 cytokine response to T. gondii challenge, and control and FIV-infected cats showed increased expression of IL2, IFNgamma, IL10, IL12, and IL6 mRNAs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Choroid plexus macrophages proliferate and release toxic factors in response to feline immunodeficiency virus
JOURNAL OF NEUROVIROLOGY, 8(3), 225–239.
author keywords: human immunodeficiency virus; brain; AIDS; neural culture; neurotoxicity
MeSH headings : Animals; CD18 Antigens / analysis; CD40 Ligand / pharmacology; Cats; Cell Division / drug effects; Cell Division / immunology; Cells, Cultured; Cerebral Cortex / cytology; Choroid Plexus / cytology; Choroid Plexus / immunology; Choroid Plexus / virology; Culture Media, Conditioned / pharmacology; Cytotoxins / immunology; Cytotoxins / metabolism; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / immunology; In Vitro Techniques; Macrophages / chemistry; Macrophages / cytology; Macrophages / virology; Neurons / virology; Specific Pathogen-Free Organisms
TL;DR:
The results suggest that lentiviral infection of the choroid plexus can induce a toxic inflammatory response that is fueled by local macrophage proliferation and may contribute to an inflammatory cascade in the brain that progresses independently of systemic and CSF viral load.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
T cells overexpressing interferon-gamma and interleukin-10 are found in both the thymus and secondary lymphoid tissues of feline immunodeficiency virus-infected cats
JOURNAL OF INFECTIOUS DISEASES, 181(2), 564–575.
MeSH headings : Animals; B-Lymphocytes / immunology; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / pathology; Gene Products, gag / metabolism; Immunodeficiency Virus, Feline / immunology; Immunohistochemistry; In Situ Hybridization; Interferon-gamma / biosynthesis; Interferon-gamma / genetics; Interleukin-10 / biosynthesis; Interleukin-10 / genetics; Lymph Nodes / immunology; Lymph Nodes / pathology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets / immunology; Thymus Gland / immunology; Thymus Gland / pathology
TL;DR:
In conclusion, overexpression of IFN-gamma and IL-10 is a feature of the thymus and secondary lymphoid tissues of FIV-infected cats and is likely to cause marked alteration in thymic lymphocyte subpopulations.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Shedding of feline immunodeficiency virus in semen of domestic cats during acute infection
American Journal of Veterinary Research, 60(2), 211–215.
Source: NC State University Libraries
Added: August 6, 2018
1998 article
Elevated interleukin-10-to-interleukin-12 ratio in feline immunodeficiency virus-infected cats predicts loss of type 1 immunity to Toxoplasma gondii
Levy, J. K., Ritchey, J. W., Rottman, J. B., Davidson, M. G., Liang, Y. H., Jordan, H. L., … Tompkins, M. B. (1998, August). JOURNAL OF INFECTIOUS DISEASES, Vol. 178, pp. 503–511.
MeSH headings : Animals; Bronchi / immunology; Cats; Cytokines / biosynthesis; Cytokines / genetics; Disease Models, Animal; Immunity; Immunodeficiency Virus, Feline / immunology; Interleukin-10 / biosynthesis; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-12 / biosynthesis; Interleukin-12 / genetics; Interleukin-12 / immunology; Lentivirus Infections / complications; Lentivirus Infections / immunology; Lymph Nodes / immunology; Male; RNA, Messenger; Toxoplasmosis / complications; Toxoplasmosis / immunology
TL;DR:
Results indicate that FIV immunodeficiency may derive from a failure to generate an IL-12-dependent type 1 response and that an elevated level of IL-10 mRNA expression is a predictor of lentivirus immunodficiency.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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