Enantiopure N-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of (-)-slaframine
ORGANIC LETTERS, 1(12), 1941–1943.
MeSH headings : Alkaloids / chemical synthesis; Mycotoxins / chemical synthesis; Pyridones / chemical synthesis; Rhizoctonia / chemistry; Stereoisomerism
topics (OpenAlex): Asymmetric Synthesis and Catalysis; Chemical synthesis and alkaloids; Coordination Chemistry and Organometallics
TL;DR:
An asymmetric synthesis of (-)-slaframine and N-acetylslafamine has been accomplished starting from an enantiopure dihydropyridone building block using an efficient phenylselenocyclocarbamation reaction.
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