Scott Knowles

Works (3)

Updated: July 5th, 2023 16:03

1998 journal article

Changes in fatty acid composition of lipids from birds, rodents, and preschool children exposed to lead

BIOLOGICAL TRACE ELEMENT RESEARCH, 61(2), 113–125.

By: S. Knowles n, W. Donaldson n & J. Andrews*

author keywords: arachidonic acid; avian; blood lead; human linoleic acid; rodent
MeSH headings : Animals; Child, Preschool; Fatty Acids / blood; Fatty Acids / metabolism; Female; Humans; Lead Poisoning / blood; Lead Poisoning / metabolism; Lipid Metabolism; Lipids / blood; Liver / metabolism; Male; Pregnancy; Rats / blood; Turkeys / blood
TL;DR: The authors propose that altered fatty acid metabolism may be responsible for some indications of Pb poisoning, and possible consequences mediated through lipid peroxidation and production of ArA-derivative eicosanoids are considered. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1996 journal article

Dietary lead alters fatty acid composition and membrane peroxidation in chick liver microsomes

POULTRY SCIENCE, 75(12), 1498–1500.

By: S. Knowles n & W. Donaldson n

author keywords: lead; peroxidation; lipids; tissue peroxides; arachidonic acid
MeSH headings : Administration, Oral; Animals; Body Weight / drug effects; Chickens; Diet; Intracellular Membranes / drug effects; Intracellular Membranes / metabolism; Lead / administration & dosage; Lead / pharmacology; Lipid Peroxidation / drug effects; Liver / anatomy & histology; Liver / drug effects; Male; Microsomes, Liver / drug effects; Microsomes, Liver / metabolism; Organ Size / drug effects; Organometallic Compounds / administration & dosage; Organometallic Compounds / pharmacology
TL;DR: Tissue peroxide levels are unaffected by the method of oral Pb administration and thus, by inference, independent of peroxide content of the feed, which is shown to be related to the consumption of preformed peroxides from the diet. (via Semantic Scholar)
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Added: August 6, 2018

1990 journal article

Dietary modification of lead toxicity: Effects on fatty acid and eicosanoid metabolism in chicks

Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology, 95(1), 99.

By: S. Knowles & W. Donaldson

Source: NC State University Libraries
Added: August 6, 2018

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