Works (6)
Updated: July 5th, 2023 16:00
2006 journal article
Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 17(3), 707–711.
author keywords: design; synthesis; efflux substrate-metal chelator conjugates; antimicrobial agents
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Bacillus subtilis / drug effects; Bacteria / drug effects; Bacteria / metabolism; Chelating Agents / chemical synthesis; Chelating Agents / pharmacology; Drug Design; Drug Resistance, Multiple, Bacterial; Escherichia coli / drug effects; Indicators and Reagents; Metals / metabolism; Microbial Sensitivity Tests; Structure-Activity Relationship
TL;DR:
A series of conjugates of metal chelators and efflux transporter substrates aimed at disrupting bacterial metal homeostasis to achieve bacterial killing were designed and synthesized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
An inexpensive carbohydrate derivative used as a chiral auxiliary in the synthesis of alpha-hydroxy carboxylic acids
TETRAHEDRON, 58(38), 7663–7679.
author keywords: chiral auxiliary; carbohydrate; asymmetric synthesis; hydroxy carboxylic acid; enolate alkylation; glycolate alkylation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 review
Recent developments in depsipeptide research
[Review of ]. CURRENT MEDICINAL CHEMISTRY, 9(4), 471–498.
MeSH headings : Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / isolation & purification; Antifungal Agents / chemistry; Antifungal Agents / isolation & purification; Antineoplastic Agents / chemistry; Antineoplastic Agents / isolation & purification; Depsides; Hydroxybenzoates / chemistry; Hydroxybenzoates / isolation & purification; Oligopeptides / chemistry; Oligopeptides / isolation & purification; Peptides / chemistry; Peptides / isolation & purification; Peptides, Cyclic / chemistry; Peptides, Cyclic / isolation & purification
TL;DR:
This review focuses on the major developments in depsipeptide research since 1995, focusing on the antiviral compounds discovered, the callipeltins and the quinoxapeptins are particularly promising due to their inhibitory activities against HIV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
The development of photometric sensors for boronic acids
BIOORGANIC CHEMISTRY, 29(5), 259–270.
author keywords: boron; boronic acid; sensor; diethanolamine; PET
MeSH headings : Azo Compounds / chemical synthesis; Azo Compounds / chemistry; Biosensing Techniques; Boronic Acids / analysis; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Electrons; Equipment Design; Esters / chemical synthesis; Evaluation Studies as Topic; Molecular Structure; Organometallic Compounds / chemical synthesis; Organometallic Compounds / chemistry; Oxidation-Reduction; Photochemistry; Photometry / methods
TL;DR:
The design and synthesis of a series of photometric chemosensors for phenylboronic acid using diethanolamine as the recognition moiety is reported, demonstrating that sensors based on several different designs can be used for the detection of boronic acids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis
Chemical & Pharmaceutical Bulletin, 48(2), 238–244.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Prodrug approaches to the improved delivery of peptide drugs
Current Pharmaceutical Design, 5(4), 265–287.
Source: NC State University Libraries
Added: August 6, 2018
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