Works (3)
Updated: July 5th, 2023 16:00
2005 journal article
Networks of coevolving sites in structural and functional domains of serpin proteins
MOLECULAR BIOLOGY AND EVOLUTION, 22(7), 1627–1634.
author keywords: serpin; factor analysis; coevolution; covariation; protein structure; mutual information
MeSH headings : Amino Acids / chemistry; Animals; Crystallography, X-Ray; Evolution, Molecular; Factor Analysis, Statistical; Multivariate Analysis; Phylogeny; Protein Conformation; Protein Folding; Protein Structure, Secondary / genetics; Sequence Analysis, Protein; Serine Proteinase Inhibitors; Serpins / chemistry; Serpins / physiology; Structure-Activity Relationship
TL;DR:
This research provides a better understanding on how protein structure evolves and elucidates the selective forces creating coevolution among protein sites.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Phylogenetic analysis of plant basic helix-loop-helix proteins
Journal of Molecular Evolution, 56(6), 742–750.
MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Genome, Plant; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Oryza / genetics; Phylogeny; Plant Proteins / chemistry; Plant Proteins / genetics; Transcription Factors / chemistry; Transcription Factors / genetics
TL;DR:
It is suggested that plant bHLH proteins are under weaker selective constraints than their animal counterparts and that lineage specific expansions and subfunctionalization have fashioned regulatory proteins for plant specific functions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal
PHYSIOLOGICAL GENOMICS, 8(1), 5–13.
author keywords: hibernation; pyruvate dehydrogenase kinase isoenzyme 4; insulin; peroxisome proliferator-activated receptor-alpha Spermophilus tridecemlineatus
MeSH headings : Adipose Tissue / chemistry; Adipose Tissue / enzymology; Adipose Tissue / physiology; Animals; Animals, Wild; Blotting, Western; Energy Metabolism / genetics; Energy Metabolism / physiology; Gene Expression Regulation / physiology; Heart / physiology; Hibernation / genetics; Hibernation / physiology; Immune Sera / metabolism; Isoenzymes / analysis; Isoenzymes / genetics; Isoenzymes / immunology; Isoenzymes / physiology; Molecular Sequence Data; Muscle, Skeletal / chemistry; Muscle, Skeletal / enzymology; Muscle, Skeletal / physiology; Myocardium / chemistry; Myocardium / enzymology; Protein Kinases / analysis; Protein Kinases / genetics; Protein Kinases / immunology; Protein Kinases / physiology; Rats; Sciuridae
TL;DR:
Examination of expression of the PDK4 gene during hibernation in heart, skeletal muscle, and white adipose tissue of the Spermophilus tridecemlineatus suggests a common signal that regulatesPDK4 expression and fuel selection During hibernation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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