Cammey Elizabeth Cole

Works (2)

Updated: July 5th, 2023 16:01

2001 review

A review of quantitative studies of benzene metabolism

[Review of ]. CRITICAL REVIEWS IN TOXICOLOGY, 31(3), 285–311.

By: M. Lovern*, C. Cole n & P. Schlosser*

MeSH headings : Animals; Benzene / administration & dosage; Benzene / metabolism; Benzene / pharmacokinetics; Enzyme Induction / drug effects; Female; Humans; In Vitro Techniques; Male; Microsomes / metabolism; Models, Theoretical
TL;DR: Results from both experimental and mathematical modeling research are considered, with particular emphasis on the last decade, and the factors that are likely to be most influential in the metabolism of benzene are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Physiologically based pharmacokinetic modeling of benzene metabolism in mice through extrapolation from in vitro to in vivo

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A, 62(6), 439–465.

By: C. Cole n, H. Tran n  & P. Schlosser n

MeSH headings : Administration, Inhalation; Algorithms; Animals; Benzene / chemistry; Benzene / metabolism; Benzene / pharmacokinetics; Benzene Derivatives / chemistry; Benzene Derivatives / metabolism; Benzene Derivatives / pharmacokinetics; Chemical Phenomena; Chemistry, Physical; Mice; Models, Biological; Risk Assessment
TL;DR: In vitro metabolic constants for humans can be extrapolated to predict the dosimetry of benzene and its metabolites in humans to better estimate the risks of adverse effects from low-level benzene exposures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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