1999 journal article

Characterization of T-lymphocytes in the anterior uvea of eyes with chronic equine recurrent uveitis


By: B. Gilger n, E. Malok n, K. Cutter n, T. Stewart n, D. Horohov* & J. Allen n

author keywords: equine; uveitis; T-lymphocyte; cytokines; immunohistochemistry; QRT-PCR
MeSH headings : Animals; Chronic Disease; Ciliary Body / immunology; Ciliary Body / pathology; Cytokines / biosynthesis; Cytokines / genetics; Horse Diseases / immunology; Horse Diseases / pathology; Horses; Immunoenzyme Techniques / veterinary; Iris / immunology; Iris / pathology; RNA, Messenger / metabolism; Recurrence; Reverse Transcriptase Polymerase Chain Reaction / veterinary; T-Lymphocyte Subsets / immunology; T-Lymphocytes / immunology; Uveitis, Anterior / immunology; Uveitis, Anterior / pathology; Uveitis, Anterior / veterinary
TL;DR: The QRT-PCR results revealed increased transcription of IL-2 and IFNgamma and low IL-4 mRNA expression in eyes with chronic ERU compared to normal eyes, demonstrating a Thelper (Th) 1-like inflammatory response in Eyes with ERU. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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