Daniel L. Feldheim

Works (40)

Updated: August 16th, 2024 13:38

2011 journal article

Growth Inhibition of Staphylococcus aureus by Mixed Monolayer Gold Nanoparticles

SMALL, 7(14), 2027–2031.

By: J. Bresee*, K. Maier *, A. Boncella*, C. Melander n & D. Feldheim n

MeSH headings : Anti-Bacterial Agents / pharmacology; Gold / pharmacology; Hydrogen Bonding / drug effects; Hydrophobic and Hydrophilic Interactions / drug effects; Ligands; Metal Nanoparticles / chemistry; Microbial Sensitivity Tests; Spectrophotometry, Infrared; Staphylococcus aureus / drug effects; Staphylococcus aureus / growth & development; Sulfhydryl Compounds / pharmacology
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Identification of antibiotics using small molecule variable ligand display on gold nanoparticles

Chemical Communications (Cambridge, England), 46(40), 7516–7518.

By: J. Bresee, K. Maier, C. Melander & D. Feldheim

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Gradient fabrication to direct transport on a surface

By: C. Gorman , D. Felheim & R. Fuierer

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Nanoparticle delivery vehicle

Washington, DC: U.S. Patent and Trademark Office.

By: S. Franzen , D. Feldheim, A. Tkachenko, M. Godek, J. Ryan & M. Anderson

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Synthesis, stability, and cellular internalization of gold nanoparticles containing mixed peptide-poly(ethylene glycol) monolayers

ANALYTICAL CHEMISTRY, 79(6), 2221–2229.

By: Y. Liu n, M. Shipton n, J. Ryan n, E. Kaufman n, S. Franzen n  & D. Feldheim n

MeSH headings : Amino Acid Sequence; Endocytosis; Gold / chemistry; HeLa Cells; Humans; Molecular Structure; Molecular Weight; Nanoparticles / chemistry; Peptides / chemical synthesis; Peptides / chemistry; Polyethylene Glycols / chemistry; Spectrometry, Fluorescence; Sulfhydryl Compounds / chemistry
TL;DR: The assembly of poly(ethylene glycol) (PEG) and mixed peptide/PEG monolayers on gold nanoparticle surfaces is described to provide useful cues in the assembly of stable peptides/gold nanoparticle bioconjugates capable of being internalized into cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Gold and silica-coated gold nanoparticles as thermographic labels for DNA detection

ANALYTICAL CHEMISTRY, 78(10), 3282–3288.

By: M. Cerruti n, M. Sauthier n, D. Leonard n, D. Liu n, G. Duscher  n, D. Feldheim n, S. Franzen n 

MeSH headings : DNA / analysis; DNA / chemistry; Gold / chemistry; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Molecular Structure; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Polylysine / chemistry; Silicon Dioxide / chemistry; Temperature; Thermography
TL;DR: The infrared emissivity of Au and silica-coated Au nanoparticles (Au NPs) deposited on indium tin oxide substrates was investigated and differences in temperature before and after laser irradiation were found to be directly proportional to the number of particles present on the slide and to the laser power used in the experiment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(19), 5148–5151.

By: W. Zeng n, T. Ballard  n, A. Tkachenko, V. Burns n, D. Feldheim n & C. Melander n

author keywords: kinamycins; lomaiviticins; DNA cleavage; diazofluorenes; antiproliferative activity
MeSH headings : Animals; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Carbazoles / pharmacology; Cell Proliferation / drug effects; DNA Damage / drug effects; Fluorenes / chemical synthesis; Fluorenes / pharmacology; HeLa Cells; Humans; Molecular Mimicry; Structure-Activity Relationship
TL;DR: Under appropriate electronic modulation, simple diazofluorene analogs recapitulate the DNA cleavage activity of kinamycin D under thiol-based reducing conditions, key to anticancer activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

RNA-mediated synthesis of palladium nanoparticles on Au surfaces

LANGMUIR, 22(13), 5862–5866.

By: D. Liu n, L. Gugliotti n, T. Wu n, M. Dolska n, A. Tkachenko, M. Shipton n, B. Eaton n, D. Feldheim n

MeSH headings : Base Sequence; Gold / chemistry; In Vitro Techniques; Metal Nanoparticles / chemistry; Metal Nanoparticles / ultrastructure; Microscopy, Electron, Scanning; Nucleic Acid Conformation; Palladium / chemistry; RNA, Catalytic / chemistry; RNA, Catalytic / metabolism; Surface Properties
TL;DR: The use of surface-bound RNA as a tool for directing the orthogonal synthesis of materials on surfaces was demonstrated and it was suggested that a single RNA molecule may be sufficient for nucleating and controlling the shapes of these particles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Transcription inhibition using oligonucleotide-modified gold nanoparticles

BIOCONJUGATE CHEMISTRY, 17(5), 1178–1183.

By: C. Agbasi-Porter n, J. Ryman-Rasmussen n, S. Franzen n  & D. Feldheim n

MeSH headings : Cell Line; DNA-Directed RNA Polymerases / genetics; DNA-Directed RNA Polymerases / metabolism; Gold / chemistry; Gold / metabolism; Humans; Metal Nanoparticles / chemistry; Oligonucleotides / chemistry; Oligonucleotides / metabolism; Promoter Regions, Genetic; Transcription, Genetic; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: The competitive binding and inhibition of T7 RNA polymerase due to specific interactions on the nanoparticle surface represents a transcription factor decoy approach in a model system and provides a basis for determining the accessibility of binding sites on nanoparticle surfaces for applications involving cell targeting or the use of nanoparticles as binding agents in solution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 patent

Electronic devices and methods using moleculary-bridged metal nanoparticles

Washington, DC: U.S. Patent and Trademark Office.

Daniel L. Feldheim; Louis C. Brousseau; James P. Novak

Source: NC State University Libraries
Added: August 6, 2018

2005 patent

Gradient fabrication to direct transport on a surface

Washington, DC: U.S. Patent and Trademark Office.

By: C. Gorman , D. Feldheim & R. Fuierer

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

RNA-mediated control of metal nanoparticle shape

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 127(50), 17814–17818.

By: L. Gugliotti n, D. Feldheim n & B. Eaton n

MeSH headings : Base Sequence; DNA, Single-Stranded / chemistry; Ligands; Molecular Sequence Data; Nanostructures / chemistry; Palladium / chemistry; Platinum / chemistry; RNA / chemistry
TL;DR: The results of this study suggest that the full-length Pdases contain active sites capable of highly specific molecular recognition of organometallic complexes as particle formation reagents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Supramolecular control of valence-tautomeric equilibrium on nanometer-scale gold clusters

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 127(15), 5328–5329.

By: S. Bin-Salamon n, S. Brewer n, S. Franzen n , D. Feldheim n, S. Lappi n & D. Shultz n 

TL;DR: The results show that surface confinement attenuates both DeltaH degrees and DeltaS degrees, and attribute these changes to a reduced accessible molecular surface area. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Attenuating negative differential resistance in an electroactive self-assembled monolayer-based junction

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126(1), 295–300.

By: R. Wassel, G. Credo, R. Fuierer, D. Feldheim & C. Gorman 

Contributors: R. Wassel, G. Credo, R. Fuierer & . al.

Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

Cellular trajectories of peptide-modified gold particle complexes: Comparison of nuclear localization signals and peptide transduction domains

BIOCONJUGATE CHEMISTRY, 15(3), 482–490.

By: A. Tkachenko, H. Xie n, Y. Liu n, D. Coleman n, J. Ryan n, W. Glomm n, M. Shipton n, S. Franzen n , D. Feldheim n

MeSH headings : 3T3 Cells; Animals; Biological Transport, Active / physiology; Cell Line, Tumor; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Gene Products, tat / chemistry; Gold / chemistry; Gold / pharmacokinetics; HeLa Cells; Humans; Macromolecular Substances; Mice; Nuclear Localization Signals / drug effects; Nuclear Localization Signals / metabolism; Peptides / chemistry; Peptides / pharmacokinetics; Protein Structure, Tertiary / physiology; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacokinetics; Temperature; Transduction, Genetic
TL;DR: Video-enhanced color differential interference contrast microscopy and transmission electron microscopy indicated that transport of nanoparticles into the cytoplasm and nucleus depends on peptide sequence and cell line, and cellular uptake of Tat PTD peptide-gold nanoparticle conjugates was temperature dependent, suggesting an endosomal pathway of uptake. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Characterization of single- and double-stranded DNA on gold surfaces

LANGMUIR, 20(25), 11134–11140.

By: S. Moses n, S. Brewer n, L. Lowe n, S. Lappi n, L. Gilvey n, M. Sauthier n, R. Tenent n, D. Feldheim n, S. Franzen n 

MeSH headings : DNA / chemistry; Gold / chemistry; Surface Properties; Temperature; Time Factors
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126(17), 5388–5395.

By: S. Kramer, H. Xie n, J. Gaff n, . Williamson n, A. Tkachenko, N. Nouri n, D. Feldheim n, D. Feldheim n

MeSH headings : Animals; Axons / drug effects; Axons / physiology; Cattle; Cell Division / drug effects; Cells, Cultured; Chromatography, High Pressure Liquid; Gold Colloid / chemistry; Gold Colloid / pharmacology; Hippocampus / cytology; Metals / chemistry; Microscopy, Fluorescence; Nanotechnology; Neurons / cytology; Neurons / drug effects; Polylysine / chemistry; Rats; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacology; Spectrophotometry
TL;DR: Surfaces patterned with proteins using the procedures described within are shown to support cell growth and are thus suitable for studies of protein-cell interactions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

RNA-mediated metal-metal bond formation in the synthesis of hexagonal palladium nanoparticles

SCIENCE, 304(5672), 850–852.

By: L. Gugliotti n, D. Feldheim n & B. Eaton n

MeSH headings : Base Sequence; Chemical Phenomena; Chemistry, Physical; Crystallization; DNA, Complementary; DNA-Directed RNA Polymerases / metabolism; Nanotubes; Palladium / chemistry; Particle Size; Polymerase Chain Reaction; RNA / chemistry; Temperature; Transcription, Genetic; Viral Proteins
TL;DR: In vitro selection techniques were used to evolve an initial library of ∼1014 unique RNA sequences through eight cycles of selection to yield several active sequence families, of which all representative members could form crystalline hexagonal palladium platelets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Critical flocculation concentrations, binding isotherms, and ligand exchange properties of peptide-modified gold nanoparticles studied by UV-visible, fluorescence, and time-correlated single photon counting spectroscopies

ANALYTICAL CHEMISTRY, 75(21), 5797–5805.

By: H. Xie n, A. Tkachenko, W. Glomm n, J. Ryan n, M. Brennaman  n, J. Papanikolas  n, S. Franzen  n, D. Feldheim n

MeSH headings : 2,2'-Dipyridyl / analogs & derivatives; 2,2'-Dipyridyl / chemistry; Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Coordination Complexes; Dithionitrobenzoic Acid / chemistry; Flocculation; Fluorescamine / chemistry; Glutathione / chemistry; Gold Colloid / chemistry; Gold Colloid / metabolism; Kinetics; Ligands; Nanotechnology / methods; Particle Size; Peptides / chemistry; Protein Binding; Rhodamines / chemistry; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / metabolism; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Succinimides / chemistry; Sulfhydryl Compounds / chemistry
TL;DR: Protocols for modifying gold nanoparticles with peptide-bovine serum albumin (BSA) conjugates are described within and TCSPC has proven to be a powerful technique for observing the microenvironment of protein-gold nanoparticle conjugacy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Laser-induced temperature jump electrochemistry on gold nanoparticle-coated electrodes

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 125(47), 14258–14259.

By: L. Lowe n, S. Brewer n, S. Kramer, R. Fuierer n, G. Qian n, C. Agbasi-Porter n, S. Moses n, S. Franzen n , D. Feldheim n

MeSH headings : DNA, Single-Stranded / analysis; DNA, Single-Stranded / chemistry; Electrochemistry / methods; Electrodes; Gold / chemistry; Indium / chemistry; Lasers; Nanotechnology; Particle Size; Surface Plasmon Resonance; Temperature; Thermography / methods
TL;DR: Laser-induced temperature jumps at gold nanoparticle-coated indium tin oxide (ITO) electrodes in contact with electrolyte solutions have been measured using temperature-sensitive redox probes and an infrared charge-coupled device. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Multifunctional gold nanoparticle-peptide complexes for nuclear targeting

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 125(16), 4700–4701.

By: A. Tkachenko, H. Xie n, D. Coleman n, W. Glomm n, J. Ryan n, M. Anderson n, S. Franzen n , D. Feldheim n

MeSH headings : Amino Acid Sequence; Cell Nucleus / metabolism; Gold / chemistry; Gold / pharmacokinetics; Humans; Molecular Sequence Data; Nanotechnology / methods; Oligopeptides / chemistry; Oligopeptides / pharmacokinetics; Particle Size; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacokinetics; Tumor Cells, Cultured
TL;DR: The ability of peptide-modified gold nanoparticles to target the nucleus of HepG2 cells was explored and nuclear targeting was more efficient when the two signals were attached to nanoparticles as separate short pieces versus one long peptide. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 patent

Nanoparticle composites and nanocapsules for guest encapsulation and methods for synthesizing same

Washington, DC: U.S. Patent and Trademark Office.

By: D. Feldheim, S. Marinakos & D. Shultz 

Source: NC State University Libraries
Added: August 6, 2018

2002 book

Metal nanoparticles: Synthesis, characterization, and applications

New York:Marcel Dekker.

By: D. Feldheim & C. Foss

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Patterning Mesoscale Gradient Structures with Self-Assembled Monolayers and Scanning Tunneling Microscopy Based Replacement Lithography

Advanced Materials, 14(2), 154–157.

By: R. Fuierer n, R. Carroll n, D. Feldheim* & C. Gorman* 

Sources: Web Of Science, Crossref
Added: August 6, 2018

2002 journal article

Supramolecular assembly on surfaces: Manipulating conductance in noncovalently modified mesoscale structures

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 124(31), 9036–9037.

By: G. Credo n, A. Boal n, K. Das n, T. Galow n, V. Rotello  n, D. Feldheim n, C. Gorman n 

Contributors: G. Credo n, A. Boal n, K. Das n & . al. n

TL;DR: With the appropriate functionalities on the complementary moieties, this work was able to increase and decrease the observed conductance in surface-bound mesoscale structures imaged by scanning tunneling microscopy (STM). (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2001 journal article

Encapsulation, permeability, and cellular uptake characteristics of hollow nanometer-sized conductive polymer capsules

JOURNAL OF PHYSICAL CHEMISTRY B, 105(37), 8872–8876.

By: S. Marinakos n, M. Anderson n, J. Ryan n, L. Martin n & D. Feldheim n

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Purification of molecularly bridged metal nanoparticle arrays by centrifugation and size exclusion chromatography

ANALYTICAL CHEMISTRY, 73(23), 5758–5761.

By: J. Novak n, C. Nickerson n, S. Franzen n  & D. Feldheim n

TL;DR: Size exclusion chromatography and centrifugation separation protocols were developed and compared for isolating enriched fractions of phenylethynyl-bridged metal nanoparticle dimers and trimers from the monomeric particle starting material. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Taking control of cells and the sun

Chemical & Engineering News, 79(13), 141.

By: D. Feldheim

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Assembly of phenylacetylene-bridged silver and gold nanoparticle arrays

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 122(16), 3979–3980.

By: J. Novak n & D. Feldheim n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Electronic and optical properties of chemically modified metal nanoparticles and molecularly bridged nanoparticle arrays

Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 104(38), 8925–8930.

By: W. McConnell, J. Novak, L. Brousseau, R. Fuierer, R. Tenent & D. Feldheim

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Nanotechnology - Flipping a molecular switch

Feldheim, D. (2000, November 2). NATURE, Vol. 408, pp. 45–46.

By: D. Feldheim n

TL;DR: Researchers have reduced the size of integrated circuits to a molecular level by harnessing chemistry, which puts a limit on the number of circuits that can be built. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Nonlinear optical properties of molecularly bridged gold nanoparticle arrays

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 122(48), 12029–12030.

By: J. Novak n, L. Brousseau n, F. Vance n, R. Johnson  n, B. Lemon n, J. Hupp  n, D. Feldheim n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Synthesis of nanometer-sized hollow polymer capsules from alkanethiol-coated gold particles

CHEMICAL COMMUNICATIONS, (9), 775–776.

By: M. Wu n, . SA O'Neill, L. Brousseau n, W. McConnell n, D. Shultz n , R. Linderman n, D. Feldheim n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Assembly of phenylacetylene-bridged gold nanocluster dimers and trimers

ADVANCED MATERIALS, 11(6), 447-+.

By: L. Brousseau n, J. Novak n, S. Marinakos n & D. Feldheim*

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Gold Nanoparticles as Templates for the Synthesis of Hollow Nanometer‐Sized Conductive Polymer Capsules

Advanced Matter, 11(1), 34–37.

By: S. Marinakos n, D. Shultz*  & D. Feldheim*

Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Gold particles as templates for the synthesis of hollow polymer capsules. Control of capsule dimensions and guest encapsulation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 121(37), 8518–8522.

By: S. Marinakos n, J. Novak n, L. Brousseau n, A. House n, E. Edeki n, J. Feldhaus n, D. Feldheim n

Source: Web Of Science
Added: August 6, 2018

1998 journal article

Electronic properties of single nanocrystals and synthesis of 1-dimensional nanocrystal arrays

Materials Research Bulletin, S(1998 Aug.), 129–137.

By: L. Brousseau, S. Marinakos, J. Novak & D. Feldheim

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Self-assembly of single electron transistors and related devices

Chemical Society Reviews, 27(1), 1–12.

By: D. Feldheim & C. Keating

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Template synthesis of one-dimensional Au, Au-poly(pyrrole), and poly(pyrrole) nanoparticle arrays

CHEMISTRY OF MATERIALS, 10(5), 1214–1219.

By: S. Marinakos n, L. Brousseau n, A. Jones  n & D. Feldheim n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

pH-Gated Single-Electron Tunneling in Chemically Modified Gold Nanoclusters

Journal of the American Chemical Society, 120(30), 7645–7646.

By: L. Brousseau n, Q. Zhao n , D. Shultz n  & D. Feldheim n

Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

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