@article{gayle_redding_2007, title={Comparison of diagnostic anaesthetic techniques of the proximal plantar metatarsus in the horse}, volume={19}, ISSN={["0957-7734"]}, DOI={10.2746/095777307X194902}, abstractNote={Equine Veterinary EducationVolume 19, Issue 4 p. 222-224 Comparison of diagnostic anaesthetic techniques of the proximal plantar metatarsus in the horse J. M. Gayle, J. M. Gayle Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA New England Equine Practice, 310 Peach Lake Road, Brewster, New York 10509, USASearch for more papers by this authorW. R. Redding, Corresponding Author W. R. Redding Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA*Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USASearch for more papers by this author J. M. Gayle, J. M. Gayle Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA New England Equine Practice, 310 Peach Lake Road, Brewster, New York 10509, USASearch for more papers by this authorW. R. Redding, Corresponding Author W. R. Redding Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA*Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USASearch for more papers by this author First published: 05 January 2010 https://doi.org/10.2746/095777307X194902Citations: 10 AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article.Citing Literature Volume19, Issue4May 2007Pages 222-224 RelatedInformation}, number={4}, journal={EQUINE VETERINARY EDUCATION}, author={Gayle, J. M. and Redding, W. R.}, year={2007}, month={May}, pages={222–224} }
 @article{rothschild_hines_breuhaus_gay_sellon_2004, title={Effects of trimethoprim-sulfadiazine on thyroid function of horses}, volume={18}, ISSN={["1939-1676"]}, DOI={10.1892/0891-6640(2004)18<370:EOTOTF>2.0.CO;2}, abstractNote={Trimethoprim-sulfadiazine was administered to horses in a randomized, placebo controlled study to determine the effects of potentiated sulfonamides on thyroid function in normal horses. The treatment group included eight horses that received trimethoprim-sulfadiazine mixed with molasses orally at 30 mg/kg once daily for eight weeks. The control group included 8 horses that received an oral placebo (flour mixed with molasses) once daily for the same period. Thyroid function was evaluated prior to initiation of treatment and after 8 weeks of treatment. Serum concentrations of total and free triiodothyronine (T3), total and free thyroxine (T4), and thyroid stimulating hormone (TSH) were determined at rest and after a thyrotropin-releasing hormone (TRH) stimulation test. There was no detectable difference between treatment and control groups.}, number={3}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Rothschild, CM and Hines, MT and Breuhaus, B and Gay, J and Sellon, DC}, year={2004}, pages={370–373} }
 @article{cole_gookin_gayle_eisemann_argenzio_blikslager_2002, title={Endoscopy via a gastric cannula to monitor the development of ulcers in the pars esophagea in pigs after consumption of a finely ground feed combined with a period of withholding of feed}, volume={63}, ISSN={["0002-9645"]}, DOI={10.2460/ajvr.2002.63.1076}, abstractNote={To develop an endoscopic technique for use in monitoring devlopment of gastric ulcers via a gastric cannula during withholding of feed and administration of a finely ground diet to pigs.6 pigs weighing between 60 and 70 kg.A gastric cannula was surgically inserted adjacent to the pars esophagea in each pig. Pigs were fed a finely ground diet for two 7-day periods that were separated by a 48-hour period during which feed was withheld. Endoscopic examination via the gastric cannula was used to monitor development of ulcers in the pars esophageal region of the pigs during the 48-hour period of feed withhold and subsequent 7-day feeding period. An ulcer score was assigned during each endoscopic examination. A final examination was performed during necropsy and compared with results for the final endoscopic examination.Consumption of a finely ground diet for 7 days resulted in progressive erosive damage to the pars esophageal region of the stomach. Further significant increases in ulcerative damage were detected after 24 and 48 hours of withholding of feed. Final examination during necropsy did not reveal significant differences from results obtained during the final endoscopic examination.Endoscopic examination via a gastric cannula was an effective means of monitoring ulcer development in the pars esophagea of pigs. Feeding a finely ground diet and withholding of feed induced endoscopically observable ulcers in the stratified squamous epithelial region of the stomach. Direct visual examination during necropsy confirmed the accuracy of endoscopic examination.}, number={8}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Cole, JT and Gookin, JL and Gayle, JM and Eisemann, JH and Argenzio, RA and Blikslager, AT}, year={2002}, month={Aug}, pages={1076–1082} }
 @article{gayle_jones_argenzio_blikslager_surgery_2002, title={Neutrophils increase paracellular permeability of restituted ischemic-injured porcine ileum}, volume={132}, ISSN={["0039-6060"]}, url={http://europepmc.org/abstract/med/12324760}, DOI={10.1067/msy.2002.125320}, abstractNote={Background. We have previously shown minimal evidence of neutrophil infiltration during early reperfusion of porcine ischemic ileum. However, we noted marked neutrophil infiltration 6 to 18 hours after ischemia during mucosal repair. We postulated such neutrophil infiltration would disrupt restituting epithelium. Methods. Pigs were pretreated with anti-CD11/CD18 monoclonal antibody, superoxide dismutase-polyethylene glycol, or saline solution before inducing 1 hour of ischemia. Pigs recovered for up to 18 hours, after which mucosal repair was assessed. Results. One hour of ischemia induced loss of 19 ± 7% of the villous epithelial surface area. Epithelial restitution covered the mucosal defect within 2 hours, although full recovery of mucosal barrier function required 6 hours. By 18 hours, a significant decrease in transepithelial electrical resistance and increase in transmucosal mannitol flux was noted despite the continued presence of complete epithelial coverage. Accumulation of neutrophils within restituting epithelium was noted on histologic examination, associated with electron-microscopic evidence of widened paracellular spaces. Pretreatment with anti-CD11/CD18 monoclonal antibody and superoxide dismutase-polyethylene glycol significantly reduced neutrophil infiltration and normalized transepithelial electrical resistance and mannitol fluxes. Conclusions. Mucosal inflammation during epithelial repair resulted in increased paracellular permeability as neutrophils traversed restituted epithelium. Blocking neutrophil adhesion or scavenging superoxide prevented mucosal dysfunction in recovering tissue. (Surgery 2002;132:461-70.)}, number={3}, journal={SURGERY}, author={Gayle, J. and Jones, S.L. and Argenzio, R.A. and Blikslager, A.T. and Surgery}, year={2002}, month={Sep}, pages={461–470} }
 @article{gayle_burrell_anderson_redding_blikslager_2001, title={Deep digital flexor tenotomy for treatment of severe laminitis in a cow}, volume={219}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2001.219.644}, abstractNote={A first-calf Guernsey cow was referred for evaluation of severe udder edema, mastitis, metritis, and ketosis. During the course of treatment, the cow became recumbent and was unable to rise. Intensive treatment resulted in the cow being able to stand for short periods with the aid of a sling. However, severe pressure necrosis of the udder and ongoing mastitis made performance of a complete mastectomy necessary. After surgery, the cow's condition improved, although assistance in standing was still required. Radiography of the distal phalanges revealed severe rotation in the right lateral and left medial digits of the hind limbs. The laminitis was nonresponsive to medical management; therefore, a deep digital flexor tenotomy was performed in the affected claws. The procedure provided almost immediate relief of signs of foot pain and resulted in ability to stand without assistance. Deep digital flexor tenotomy should be considered when treating cows with severe laminitis.}, number={5}, journal={JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Gayle, JM and Burrell, GA and Anderson, KL and Redding, WR and Blikslager, AT}, year={2001}, month={Sep}, pages={644–646} }
 @article{gayle_macharg_smallwood_2001, title={Strangulating obstruction caused by intestinal herniation through the proximal aspect of the cecocolic fold in 9 horses}, volume={30}, ISSN={["0161-3499"]}, DOI={10.1053/jvet.2001.20342}, abstractNote={To report the clinical and surgical findings and outcome for horses with strangulating obstruction caused by herniation through the proximal aspect of the cecocolic fold.Retrospective study.Nine horses.Medical records were reviewed for clinical signs, surgical findings and technique, and outcome. Cadaver ponies and necropsy specimens were also used to study the regional anatomy of the cecocolic fold.The ileum and distal jejunum were strangulated in 8 horses, whereas in 1 horse the small intestine and the left ascending colons were incarcerated in a rent in the cecocolic fold. Two horses were euthanatized at surgery, 6 horses had a small intestinal resection (mean length, 3 m; range, 1.5-6.4 m) and an end-to-side jejunocecostomy, and the entrapment was reduced without resection in the horse that had small intestine and ascending colon incarceration; cecocolic fold defects were not closed. One horse was euthanatized 36 hours after surgery because of endotoxemia. Six horses were discharged; 4 were available for long-term follow-up, of which 2 were euthanatized, and 2 were euthanatized 12 and 18 months after surgery because of colic signs. Variations in thickness of the cecocolic fold were observed in specimens obtained from necropsy of other horses and ponies.Reasons for this defect are unknown, although observed anatomic differences in cecocolic fold thickness may contribute to the development of defects.Reduction of the entrapped bowel is easiest when traction is placed on the bowel at a 90 degrees to the base of the cecum. Intestinal incarceration through rents within the proximal part of the cecocolic fold should be considered as a differential diagnosis for strangulating obstruction in horses.}, number={1}, journal={VETERINARY SURGERY}, author={Gayle, JM and Macharg, MA and Smallwood, JE}, year={2001}, pages={40–43} }
 @article{gayle_blikslager_bowman_2000, title={Mesenteric rents as a source of small intestinal strangulation in horses: 15 cases (1990-1997)}, volume={216}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2000.216.1446}, abstractNote={To describe the clinical findings in horses with small intestinal strangulation through mesenteric rents, and to determine the recurrence and survival rates after surgery.Retrospective study.15 horses with small intestinal obstruction via a mesenteric rent.Medical records of horses with obstruction of the small intestine via a mesenteric rent between January 1990 and December 1997 were reviewed. The signalment, history, initial physical examination findings, results of abdominocentesis, and clinical laboratory values were recorded. Surgical findings, including location of the mesenteric rent and surgical procedure performed, were recorded. Short- and long-term survival rates were calculated.Most mesenteric rents were located in the mesentery of the small intestine (13 horses). Two horses had multiple mesenteric defects. Seven horses were euthanatized at surgery because of an inability to reduce the entrapped intestine (3 horses), uncontrollable hemorrhage (2), inability to close the rent (1), and the amount of compromised intestine involved (1). Seven horses required intestinal resection and anastomosis. The median length of intestine resected was 2.6 m (range, 0.6 to 4.5 m). The mesenteric rents created during resection were not closed in 2 horses. One of these 2 horses subsequently developed a strangulating obstruction through the open rent. Seven of 15 horses in our study were discharged from the hospital (i.e., short-term survival rate of 47% [7/15]). Long-term follow-up information was available for 5 of the 7 horses (follow-up duration of 5 months to 9 years), of which 2 died as a result of colic, and 1 horse was euthanatized because of severe arthritis (i.e., long-term survival rate of 40% [2/5]).Inability to reduce the intestinal obstruction, severe hemorrhage from the mesentery, and the length of intestine involved are the main factors that decrease survival rates in horses with small intestinal strangulation caused by mesenteric rents.}, number={9}, journal={JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Gayle, JM and Blikslager, AT and Bowman, KF}, year={2000}, month={May}, pages={1446–1449} }
 @article{gayle_redding_vacek_bowman_1999, title={Diagnosis and surgical treatment of periapical infection of the third mandibular molar in five horses}, volume={215}, number={6}, journal={Journal of the American Veterinary Medical Association}, author={Gayle, J. M. and Redding, W. R. and Vacek, J. R. and Bowman, K. F.}, year={1999}, pages={829–832} }
 @article{gayle_cohen_chaffin_1998, title={Factors associated with survival in septicemic foals: 65 cases (1988-1995)}, volume={12}, ISSN={["0891-6640"]}, DOI={10.1111/j.1939-1676.1998.tb02109.x}, abstractNote={In order to identify variables obtained at admission that could be used to predict survival in septicemic foals, medical records of 65 foals diagnosed with septicemia were reviewed. Initially, variables were analyzed independently (univariate analysis) for association with survival. Of the physical examination and historical data examined using univariate analysis, the ability to stand at admission, respiratory rate ≥ 60 breaths per minute (bpm), and normal-appearing mucous membranes were significantly associated with survival. Foals with history of induced parturition were significantly less likely to survive. The following hematologic and serum biochemical variables determined at admission were significantly associated with survival: white blood cell count a 6,000 cells/μL, neutrophil count <4,000 cells/μL, serum albumin concentration <2.2 g/dL, serum glucose concentration <120 mg/ dL, blood pH ≥ 7.35, and positive base excess. The administration of plasma at admission was significantly associated with survival. Stepwise multiple logistic regression analysis was performed to evaluate the association between survival and variables identified as significantly associated with survival in bivariate analysis. The final multivariate model selected included the variables standing, duration of clinical signs (24-hour intervals) prior to admission, respiratory rate a 60 bpm, neutropenia (> 4,000 cells/μL), and neonatal age category. The probability of survival was significantly increased for foals that were standing, had a respiratory rate a 60 bpm, and that had a neutrophil count <4,000 cells/μL at admission. Probability of survival was significantly decreased for foals that had a longer duration of clinical signs prior to admission. For each 24 hours of duration, the estimated risk of death was increased by 5.8-fold.}, number={3}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Gayle, JM and Cohen, ND and Chaffin, MK}, year={1998}, pages={140–146} }