@article{gayle_redding_2007, title={Comparison of diagnostic anaesthetic techniques of the proximal plantar metatarsus in the horse}, volume={19}, ISSN={["0957-7734"]}, DOI={10.2746/095777307X194902}, abstractNote={Equine Veterinary EducationVolume 19, Issue 4 p. 222-224 Comparison of diagnostic anaesthetic techniques of the proximal plantar metatarsus in the horse J. M. Gayle, J. M. Gayle Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA New England Equine Practice, 310 Peach Lake Road, Brewster, New York 10509, USASearch for more papers by this authorW. R. Redding, Corresponding Author W. R. Redding Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA*Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USASearch for more papers by this author J. M. Gayle, J. M. Gayle Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA New England Equine Practice, 310 Peach Lake Road, Brewster, New York 10509, USASearch for more papers by this authorW. R. Redding, Corresponding Author W. R. Redding Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA*Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USASearch for more papers by this author First published: 05 January 2010 https://doi.org/10.2746/095777307X194902Citations: 10 AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article.Citing Literature Volume19, Issue4May 2007Pages 222-224 RelatedInformation}, number={4}, journal={EQUINE VETERINARY EDUCATION}, author={Gayle, J. M. and Redding, W. R.}, year={2007}, month={May}, pages={222–224} }
 @article{rothschild_hines_breuhaus_gay_sellon_2004, title={Effects of trimethoprim-sulfadiazine on thyroid function of horses}, volume={18}, ISSN={["1939-1676"]}, DOI={10.1892/0891-6640(2004)18<370:EOTOTF>2.0.CO;2}, abstractNote={Trimethoprim-sulfadiazine was administered to horses in a randomized, placebo controlled study to determine the effects of potentiated sulfonamides on thyroid function in normal horses. The treatment group included eight horses that received trimethoprim-sulfadiazine mixed with molasses orally at 30 mg/kg once daily for eight weeks. The control group included 8 horses that received an oral placebo (flour mixed with molasses) once daily for the same period. Thyroid function was evaluated prior to initiation of treatment and after 8 weeks of treatment. Serum concentrations of total and free triiodothyronine (T3), total and free thyroxine (T4), and thyroid stimulating hormone (TSH) were determined at rest and after a thyrotropin-releasing hormone (TRH) stimulation test. There was no detectable difference between treatment and control groups.}, number={3}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Rothschild, CM and Hines, MT and Breuhaus, B and Gay, J and Sellon, DC}, year={2004}, pages={370–373} }
 @article{cole_gookin_gayle_eisemann_argenzio_blikslager_2002, title={Endoscopy via a gastric cannula to monitor the development of ulcers in the pars esophagea in pigs after consumption of a finely ground feed combined with a period of withholding of feed}, volume={63}, ISSN={["0002-9645"]}, DOI={10.2460/ajvr.2002.63.1076}, abstractNote={Abstract}, number={8}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Cole, JT and Gookin, JL and Gayle, JM and Eisemann, JH and Argenzio, RA and Blikslager, AT}, year={2002}, month={Aug}, pages={1076–1082} }
 @article{gayle_jones_argenzio_blikslager_surgery_2002, title={Neutrophils increase paracellular permeability of restituted ischemic-injured porcine ileum}, volume={132}, ISSN={["0039-6060"]}, url={http://europepmc.org/abstract/med/12324760}, DOI={10.1067/msy.2002.125320}, abstractNote={BACKGROUND
We have previously shown minimal evidence of neutrophil infiltration during early reperfusion of porcine ischemic ileum. However, we noted marked neutrophil infiltration 6 to 18 hours after ischemia during mucosal repair. We postulated such neutrophil infiltration would disrupt restituting epithelium.


METHODS
Pigs were pretreated with anti-CD11/CD18 monoclonal antibody, superoxide dismutase-polyethylene glycol, or saline solution before inducing 1 hour of ischemia. Pigs recovered for up to 18 hours, after which mucosal repair was assessed.


RESULTS
One hour of ischemia induced loss of 19 +/- 7% of the villous epithelial surface area. Epithelial restitution covered the mucosal defect within 2 hours, although full recovery of mucosal barrier function required 6 hours. By 18 hours, a significant decrease in transepithelial electrical resistance and increase in transmucosal mannitol flux was noted despite the continued presence of complete epithelial coverage. Accumulation of neutrophils within restituting epithelium was noted on histologic examination, associated with electron-microscopic evidence of widened paracellular spaces. Pretreatment with anti-CD11/CD18 monoclonal antibody and superoxide dismutase-polyethylene glycol significantly reduced neutrophil infiltration and normalized transepithelial electrical resistance and mannitol fluxes.


CONCLUSIONS
Mucosal inflammation during epithelial repair resulted in increased paracellular permeability as neutrophils traversed restituted epithelium. Blocking neutrophil adhesion or scavenging superoxide prevented mucosal dysfunction in recovering tissue.}, number={3}, journal={SURGERY}, author={Gayle, J. and Jones, S.L. and Argenzio, R.A. and Blikslager, A.T. and Surgery}, year={2002}, month={Sep}, pages={461–470} }
 @article{gayle_burrell_anderson_redding_blikslager_2001, title={Deep digital flexor tenotomy for treatment of severe laminitis in a cow}, volume={219}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2001.219.644}, abstractNote={A first-calf Guernsey cow was referred for evaluation of severe udder edema, mastitis, metritis, and ketosis. During the course of treatment, the cow became recumbent and was unable to rise. Intensive treatment resulted in the cow being able to stand for short periods with the aid of a sling. However, severe pressure necrosis of the udder and ongoing mastitis made performance of a complete mastectomy necessary. After surgery, the cow's condition improved, although assistance in standing was still required. Radiography of the distal phalanges revealed severe rotation in the right lateral and left medial digits of the hind limbs. The laminitis was nonresponsive to medical management; therefore, a deep digital flexor tenotomy was performed in the affected claws. The procedure provided almost immediate relief of signs of foot pain and resulted in ability to stand without assistance. Deep digital flexor tenotomy should be considered when treating cows with severe laminitis.}, number={5}, journal={JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Gayle, JM and Burrell, GA and Anderson, KL and Redding, WR and Blikslager, AT}, year={2001}, month={Sep}, pages={644–646} }
 @article{gayle_macharg_smallwood_2001, title={Strangulating obstruction caused by intestinal herniation through the proximal aspect of the cecocolic fold in 9 horses}, volume={30}, ISSN={["0161-3499"]}, DOI={10.1053/jvet.2001.20342}, abstractNote={Objective—To report the clinical and surgical findings and outcome for horses with strangulating obstruction caused by herniation through the proximal aspect of the cecocolic fold.}, number={1}, journal={VETERINARY SURGERY}, author={Gayle, JM and Macharg, MA and Smallwood, JE}, year={2001}, pages={40–43} }
 @article{gayle_blikslager_bowman_2000, title={Mesenteric rents as a source of small intestinal strangulation in horses: 15 cases (1990-1997)}, volume={216}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2000.216.1446}, abstractNote={Abstract}, number={9}, journal={JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Gayle, JM and Blikslager, AT and Bowman, KF}, year={2000}, month={May}, pages={1446–1449} }
 @article{gayle_redding_vacek_bowman_1999, title={Diagnosis and surgical treatment of periapical infection of the third mandibular molar in five horses}, volume={215}, number={6}, journal={Journal of the American Veterinary Medical Association}, author={Gayle, J. M. and Redding, W. R. and Vacek, J. R. and Bowman, K. F.}, year={1999}, pages={829–832} }
 @article{gayle_cohen_chaffin_1998, title={Factors associated with survival in septicemic foals: 65 cases (1988-1995)}, volume={12}, ISSN={["0891-6640"]}, DOI={10.1111/j.1939-1676.1998.tb02109.x}, abstractNote={In order to identify variables obtained at admission that could be used to predict survival in septicemic foals, medical records of 65 foals diagnosed with septicemia were reviewed. Initially, variables were analyzed independently (univariate analysis) for association with survival. Of the physical examination and historical data examined using univariate analysis, the ability to stand at admission, respiratory rate ≥ 60 breaths per minute (bpm), and normal‐appearing mucous membranes were significantly associated with survival. Foals with history of induced parturition were significantly less likely to survive. The following hematologic and serum biochemical variables determined at admission were significantly associated with survival: white blood cell count a 6,000 cells/μL, neutrophil count <4,000 cells/μL, serum albumin concentration <2.2 g/dL, serum glucose concentration <120 mg/ dL, blood pH ≥ 7.35, and positive base excess. The administration of plasma at admission was significantly associated with survival. Stepwise multiple logistic regression analysis was performed to evaluate the association between survival and variables identified as significantly associated with survival in bivariate analysis. The final multivariate model selected included the variables standing, duration of clinical signs (24‐hour intervals) prior to admission, respiratory rate a 60 bpm, neutropenia (> 4,000 cells/μL), and neonatal age category. The probability of survival was significantly increased for foals that were standing, had a respiratory rate a 60 bpm, and that had a neutrophil count <4,000 cells/μL at admission. Probability of survival was significantly decreased for foals that had a longer duration of clinical signs prior to admission. For each 24 hours of duration, the estimated risk of death was increased by 5.8‐fold.}, number={3}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Gayle, JM and Cohen, ND and Chaffin, MK}, year={1998}, pages={140–146} }