Works (3)

Updated: July 5th, 2023 16:02

2000 journal article

Synthesis and properties of uniquely modified oligoribonucleotides: Yeast tRNA(Phe) fragments with 6-methyluridine and 5,6-dimethyluridine at site-specific positions

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 19(3), 515–531.

By: E. Sochacka*, G. Czerwinska*, R. Guenther n, R. Cain n, P. Agris n & A. Malkiewicz*

MeSH headings : Anticodon; Magnetic Resonance Spectroscopy; Methylation; Molecular Conformation; Oligoribonucleotides / chemical synthesis; Oligoribonucleotides / chemistry; Organophosphorus Compounds / chemistry; RNA, Transfer, Phe / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Uridine / analogs & derivatives; Uridine / chemistry; Yeasts / chemistry
TL;DR: Stability when the modified uridine is in a loop is sequence context dependent, and can not, at this time, be predicted from the location in the loop, but decrease in RNA duplex stability is predictable. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Single atom modification (O -> S) of tRNA confers ribosome binding

RNA, 5(2), 188–194.

By: S. Ashraf n, E. Sochacka*, R. Cain n, R. Guenther n, A. Malkiewicz* & P. Agris n

author keywords: 2-thiouridine; anticodon conformation; anticodon stem loop analogs; nucleoside modifications; ribosome; translation; tRNA(LyS)
MeSH headings : Aldehydes / metabolism; Anticodon / genetics; Butanones; Escherichia coli / metabolism; Humans; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation / genetics; Nucleic Acid Hybridization / genetics; RNA, Fungal / genetics; RNA, Transfer, Lys / chemistry; RNA, Transfer, Lys / genetics; Ribosomes / metabolism; Spectrum Analysis; Temperature; Thiouridine / analogs & derivatives; Thiouridine / metabolism
TL;DR: It is concluded that s2U34 in tRNALysSUU and in other s2 U34-containing tRNAs is critical for generating an anticodon conformation that leads to effective codon interaction in all organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Structural and functional roles of the N1-and N3-protons of Psi at tRNA's position 39

NUCLEIC ACIDS RESEARCH, 27(17), 3543–3549.

By: C. Yarian n, M. Basti*, R. Cain n, G. Ansari n, R. Guenther n, E. Sochacka*, G. Czerwinska*, A. Malkiewicz*, P. Agris*

MeSH headings : Anticodon / chemistry; Genes, Fungal / genetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Protons; Pseudouridine / chemistry; RNA, Ribosomal, 16S / chemistry; RNA, Transfer, Phe / chemistry; Ribosomes / chemistry; Structure-Activity Relationship; Temperature; Thermodynamics; Uridine / chemistry; Yeasts / genetics
Source: Web Of Science
Added: August 6, 2018

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