Works (13)
Updated: July 5th, 2023 16:01
2020 journal article
Engineered Cartilage from Human Chondrocytes with Homozygous Knockout of Cell Cycle Inhibitor p21
TISSUE ENGINEERING PART A, 26(7-8), 441–449.
author keywords: genome editing; CRISPR; regeneration; tissue engineering
MeSH headings : Blotting, Western; Chondrocytes / cytology; Chondrocytes / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Cyclin-Dependent Kinase Inhibitor p21 / genetics; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; Gene Editing; Glycosaminoglycans / metabolism; Humans; Immunohistochemistry; Polymerase Chain Reaction; Tissue Engineering / methods
doi.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 9, 2019
2015 journal article
Early-life dietary spray-dried plasma influences immunological and intestinal injury responses to later-life Salmonella typhimurium challenge
BRITISH JOURNAL OF NUTRITION, 113(5), 783–793.
author keywords: Spray-dried plasma; Early-life nutrition; Salmonella typhimurium; Intestinal inflammation; Mucosal immunity; Intestinal permeability; Weaning
MeSH headings : Animals; Biomarkers / blood; Biomarkers / metabolism; Blood Proteins / administration & dosage; Blood Proteins / therapeutic use; Crosses, Genetic; Cytokines / blood; Cytokines / metabolism; Diet / adverse effects; Diet / veterinary; Energy Intake; Enterocolitis / immunology; Enterocolitis / microbiology; Enterocolitis / prevention & control; Enterocolitis / veterinary; Feces / microbiology; Female; Ileum / immunology; Ileum / metabolism; Ileum / microbiology; Ileum / pathology; Immunity, Mucosal; Immunotherapy / adverse effects; Immunotherapy / veterinary; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Male; Salmonella Infections, Animal / immunology; Salmonella Infections, Animal / metabolism; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / growth & development; Salmonella typhimurium / immunology; Salmonella typhimurium / isolation & purification; Sus scrofa; Swine; Swine Diseases / immunology; Swine Diseases / metabolism; Swine Diseases / microbiology; Swine Diseases / prevention & control; Weaning; Weight Gain
TL;DR:
Results indicate that inclusion of SDP in PW diets can have an influence on subsequent immunological and intestinal injury responses induced by later-life S. typhimurium challenge.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Bone marrow-derived cells participate in the formation of normal and neoplastic lung stroma
Anticancer Research, 33(3), 831–836.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Evaluation of a side population of canine lymphoma cells using Hoechst 33342 dye
JOURNAL OF VETERINARY SCIENCE, 14(4), 481–486.
author keywords: dog; flow cytometry; Hoechst 33342; lymphoma; side population
MeSH headings : Animals; Benzimidazoles / metabolism; Cell Line, Tumor; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Flow Cytometry / methods; Flow Cytometry / veterinary; Fluorescent Dyes / metabolism; Gene Expression Regulation, Developmental; Lymphoma / diagnosis; Lymphoma / drug therapy; Lymphoma / pathology; Lymphoma / veterinary; Neoplastic Stem Cells / drug effects; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Side-Population Cells / drug effects; Side-Population Cells / metabolism; Side-Population Cells / pathology
TL;DR:
The present study was performed to explore the potential value of a side population (SP) assay for identifying and characterizing putative CSCs among canine lymphoma cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Morphologic and Molecular Analysis of 39 Spontaneous Feline Pulmonary Carcinomas
VETERINARY PATHOLOGY, 49(6), 971–978.
author keywords: cat; lung cancer; immunohistochemistry; thyroid transcription factor-1; surfactant protein a; epidermal growth factor receptor; p53
MeSH headings : Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Adenocarcinoma / veterinary; Adenocarcinoma, Bronchiolo-Alveolar / metabolism; Adenocarcinoma, Bronchiolo-Alveolar / pathology; Adenocarcinoma, Bronchiolo-Alveolar / veterinary; Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Carcinoma, Adenosquamous / metabolism; Carcinoma, Adenosquamous / pathology; Carcinoma, Adenosquamous / veterinary; Cat Diseases / genetics; Cat Diseases / metabolism; Cat Diseases / pathology; Cats; DNA, Neoplasm / chemistry; DNA, Neoplasm / genetics; ErbB Receptors / genetics; ErbB Receptors / metabolism; Female; Immunohistochemistry / veterinary; Incidence; Lung Neoplasms / metabolism; Lung Neoplasms / pathology; Lung Neoplasms / veterinary; Male; Neoplasm Metastasis; North Carolina; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Pulmonary Surfactant-Associated Protein A / genetics; Pulmonary Surfactant-Associated Protein A / metabolism; Sequence Analysis, DNA / veterinary; Thyroid Nuclear Factor 1; Transcription Factors / genetics; Transcription Factors / metabolism; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism
TL;DR:
Results indicate that primary lung carcinomas are rare but aggressive tumors in cats, thereby warranting further studies on molecular carcinogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2010 journal article
Characterization of side population cells in human malignant mesothelioma cell lines
LUNG CANCER, 70(2), 146–151.
author keywords: Mesothelioma; Side population; Cancer stem cell; Hoechst 33342; Tumorigenicity; Flow cytometry
MeSH headings : Animals; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cisplatin / pharmacology; Feasibility Studies; Flow Cytometry; Gene Expression Regulation, Developmental; Humans; Mesothelioma / diagnosis; Mesothelioma / drug therapy; Mesothelioma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells / drug effects; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Side-Population Cells / drug effects; Side-Population Cells / metabolism; Side-Population Cells / pathology
TL;DR:
The data indicated that SP assay may not be appropriate for enriching putative CSCs in HMM cell lines, and thus warrants the development of a novel tool for mesothelial CSC study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
CANCER LETTERS, 278(1), 49–55.
author keywords: Malignant mesothelioma; Insulin-like growth factor 1 receptor; AG1024; Cisplatin; Chemoresistance
MeSH headings : Antineoplastic Agents / therapeutic use; Apoptosis / drug effects; Cell Division / drug effects; Cell Line, Tumor / drug effects; Cisplatin / therapeutic use; Humans; Mesothelioma / drug therapy; Pleural Neoplasms / drug therapy; Receptor, IGF Type 1 / antagonists & inhibitors; Signal Transduction / drug effects; Tyrphostins / therapeutic use
TL;DR:
This study supports the conjecture that inhibition of the IGF-1R pathway may be a useful target for reducing toxicity and alleviating chemoresistance to traditional anticancer drugs in HMM patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Production of germline chimeric chickens following the administration of a busulfan emulsion
MOLECULAR REPRODUCTION AND DEVELOPMENT, 70(4), 438–444.
author keywords: germline; chimera; busulfan; chicken
MeSH headings : Alkylating Agents / pharmacology; Animals; Busulfan / pharmacology; Chick Embryo; Chickens / genetics; Chimera / genetics; Female; Male; Ovum / drug effects; Spermatozoa / drug effects
TL;DR:
Results demonstrated that the administration of a busulfan emulsion into the egg yolk of unincubated eggs improved the depletion of endogenous PGCs in the embryo and enhanced the efficiency of germline chimera production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 patent
Methods for gamete production in birds
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2001 review
Comparative development of avian primordial germ cells and production of germ line chimeras
[Review of ]. AVIAN AND POULTRY BIOLOGY REVIEWS, 12(4), 151–168.
author keywords: primordial germ cells; embryo; chimeras; chick; turkey; quail; migration; transgenic
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2000 journal article
Expression and purification of biologically active recombinant quail stem cell factor in E-coli
CELL BIOLOGY INTERNATIONAL, 24(5), 311–317.
author keywords: quail; stem cell factor; SCF; his-tagged; recombinant protein
MeSH headings : Animals; Biological Assay; Blotting, Western; Cell Survival / drug effects; Cells, Cultured; Chick Embryo; Chromatography, Affinity; Ciliary Neurotrophic Factor / pharmacology; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli / genetics; Escherichia coli / metabolism; Ganglia, Spinal / cytology; Ganglia, Spinal / drug effects; Neurons / cytology; Neurons / drug effects; Quail / genetics; Recombinant Fusion Proteins / biosynthesis; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / isolation & purification; Recombinant Fusion Proteins / pharmacology; Stem Cell Factor / biosynthesis; Stem Cell Factor / genetics; Stem Cell Factor / isolation & purification; Stem Cell Factor / pharmacology
TL;DR:
The availability of quail SCF will be a valuable tool to further resolve the function of stem cell factor in birds as it improved neuronal survival and survival and resembled the soluble form of SCF.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2000 patent
Methods for gamete production in birds
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Characterization of stage-specific embryonic antigen-1 (SSEA-1) expression during early development of the turkey embryo
International Journal of Developmental Biology, 43(4), 349–356.
Source: NC State University Libraries
Added: August 6, 2018
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