Works (1)
Updated: July 5th, 2023 16:02
1999 journal article
Progressive expansion of an L-selectin-negative CD8 cell with anti-feline immunodeficiency virus (FIV) suppressor function in the circulation of FIV-infected cats
JOURNAL OF INFECTIOUS DISEASES, 180(5), 1503–1513.
MeSH headings : Animals; CD8-Positive T-Lymphocytes / immunology; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Immunodeficiency Virus, Feline / immunology; Immunophenotyping; Integrins / metabolism; L-Selectin / analysis; Leukocytes, Mononuclear / immunology; Lymph Nodes / immunology; T-Lymphocyte Subsets / immunology; T-Lymphocytes, Regulatory / immunology
TL;DR:
The progressive expansion of the CD8alpha+betaloCD62L- effector subset cells in FIV-infected cats parallels that seen in human immunodeficiency virus (HIV)-infected patients, suggesting that failure in homeostatic mechanisms regulating lymphocyte activation or trafficking (or both) may be a consequence of both HIV and FIV infections.
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